Evidence map›Paper›PMID 41561010›Full record

ArticleRSC advances2026

Synthesis and binding studies of two new coumarin-squaramide-based receptors for NSAIDs.

Luca Mancini, Filippo Ingargiola, Giampaolo Barone, Patrizia Rossi, Mauro Formica, Eleonora Macedi, Martina Lippi, Luca Giorgi, Luca Prodi, Vieri Fusi and 1 more

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luca ManciniDepartment of Pure and Applied Sciences, University of Urbino Via Ca' Le Suore 2-4 Urbino 61029 Italy luca.giorgi@uniurb.it vieri.fusi@uniurb.it.
Filippo IngargiolaDepartment of Chemistry "Giacomo Ciamician", Università degli Studi di Bologna Via Selmi 2 40126 Bologna Italy luca.prodi@unibo.it.
Giampaolo BaroneDepartment of Biological, Chemical and Pharmaceutical Sciences and Technologies (STeBiCeF), University of Palermo Viale delle Scienze, Edificio 17 90128 Palermo Italy.ORCID https://orcid.org/0000-0001-8773-2359
Patrizia RossiDepartment of Industrial Engineering, University of Florence Via S. Marta 3 Florence 5013 Italy.ORCID https://orcid.org/0000-0002-6316-338X
Mauro FormicaDepartment of Pure and Applied Sciences, University of Urbino Via Ca' Le Suore 2-4 Urbino 61029 Italy luca.giorgi@uniurb.it vieri.fusi@uniurb.it.ORCID https://orcid.org/0000-0002-2087-4624
Eleonora MacediDepartment of Pure and Applied Sciences, University of Urbino Via Ca' Le Suore 2-4 Urbino 61029 Italy luca.giorgi@uniurb.it vieri.fusi@uniurb.it.ORCID https://orcid.org/0000-0003-0251-901X
Martina LippiDepartment of Industrial Engineering, University of Florence Via S. Marta 3 Florence 5013 Italy.
Luca GiorgiDepartment of Pure and Applied Sciences, University of Urbino Via Ca' Le Suore 2-4 Urbino 61029 Italy luca.giorgi@uniurb.it vieri.fusi@uniurb.it.ORCID https://orcid.org/0000-0001-5734-2835
Luca ProdiDepartment of Chemistry "Giacomo Ciamician", Università degli Studi di Bologna Via Selmi 2 40126 Bologna Italy luca.prodi@unibo.it.ORCID https://orcid.org/0000-0002-1630-8291
Vieri FusiDepartment of Pure and Applied Sciences, University of Urbino Via Ca' Le Suore 2-4 Urbino 61029 Italy luca.giorgi@uniurb.it vieri.fusi@uniurb.it.ORCID https://orcid.org/0000-0002-7627-8637
Daniele PaderniDepartment of Pure and Applied Sciences, University of Urbino Via Ca' Le Suore 2-4 Urbino 61029 Italy luca.giorgi@uniurb.it vieri.fusi@uniurb.it.ORCID https://orcid.org/0000-0003-4598-5117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two new squaramide-based receptors containing coumarin units have been synthesized and characterized in both solution and solid states. L1 (3-(benzylamino)-4-((2-oxo-4-(trifluoromethyl)-2

Identifiers

PMID41561010
PMCPMC12814399

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.