Evidence map›Paper›PMID 41560969›Full record

ArticleJournal of experimental orthopaedics2026

Objective functional performance 1 year after total knee arthroplasty does not differ for patients with symptoms of anxiety, depression or pain catastrophizing: A prospective study of 289 patients.

Margot B Aalders, Jelle P van der List, Stef Daniel, Gino M M J Kerkhoffs, Job N Doornberg, Ruurd L Jaarsma, Lucien C M Keijser, Joyce L Benner

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Margot B AaldersDepartment of Orthopaedic Surgery and Sports Medicine Amsterdam UMC, Location AMC Amsterdam the Netherlands.ORCID https://orcid.org/0009-0007-7060-8723
Jelle P van der ListCentre for Orthopedic Research Alkmaar (CORAL) Alkmaar the Netherlands.ORCID https://orcid.org/0000-0002-7940-5152
Stef DanielCentre for Orthopedic Research Alkmaar (CORAL) Alkmaar the Netherlands.
Gino M M J KerkhoffsDepartment of Orthopaedic Surgery and Sports Medicine Amsterdam UMC, Location AMC Amsterdam the Netherlands.
Job N DoornbergDepartment of Orthopaedic Surgery University Medical Centre Groningen Groningen the Netherlands.
Ruurd L JaarsmaDepartment of Orthopaedic Surgery, Flinders Medical Centre Flinders University Adelaide South Australia Australia.
Lucien C M KeijserCentre for Orthopedic Research Alkmaar (CORAL) Alkmaar the Netherlands.
Joyce L BennerCentre for Orthopedic Research Alkmaar (CORAL) Alkmaar the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Preoperative anxiety, depression and pain catastrophizing (PC) symptoms are associated with inferior patient-reported outcomes after total knee arthroplasty (TKA). It remains unclear whether such differences also exist for objective outcomes such as strength, range of motion (ROM) and timed up and go (TUG). This study aimed to investigate whether objective functional performance differs up to 12 months postoperatively in patients with these psychological symptoms. Methods: A prospective cohort of 289 TKA patients was analysed (55% female, age 71 [65-76]). Anxiety (21%), depression (17%) and PC (14%) were assessed preoperatively using the Hospital Anxiety and Depression Scale and Pain Catastrophizing Scale. Objective outcomes consisting of maximum strength (strength), strength endurance (SE), ROM and TUG were measured preoperatively and at 6 and 12 months postoperatively. Between-group comparisons were adjusted for confounders (age, sex, American Society of Anesthesiologists, body mass index, surgical approach, baseline functional performance) using multivariable regression. Results: Preoperatively, mainly anxiety- and depression-symptoms were associated with lower strength and SE (all Conclusion: Although preoperative psychological symptoms are associated with poorer objective outcomes, these differences resolve by 6-12 months postoperative follow-up. After 1 year, similar objective outcomes are attained for patients with symptoms of anxiety, depression or PC. Interpreting this in the bigger scope, the importance of integrating psychological support into the perioperative pathway to align subjective and objective outcomes is underlined. Level of Evidence: Level II, prognostic cohort study.

Indexed as

functional performanceknee arthroplastymental healthrange of motionstrengthtimed up and go

Identifiers

PMID41560969
PMCPMC12814217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.