Evidence map›Paper›PMID 41560960›Full record

ReviewAesthetic surgery journal. Open forum2026

Efficacy and Safety of Hyaluronic Acid Fillers for Horizontal Neck Lines: A Systematic Review and Meta-Analysis.

Zhen Yu Wong, Shradha Limbu, George Karanasios, Fabio Monks, Ryan Faderani, Muholan Kanapathy, Afshin Mosahebi

Abstract readReview
In one paragraph

Review in Aesthetic surgery journal. Open forum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shradha Limbu
George Karanasios
Fabio Monks
Ryan Faderani
Muholan Kanapathy
Afshin Mosahebi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Horizontal neck lines are a common aesthetic concern among aging and younger populations. Hyaluronic acid (HA) fillers are increasingly used in this region, yet their effectiveness, safety, and optimal application strategies remain under-investigated. This systematic review and meta-analysis, conducted in accordance with PRISMA guidelines and registered with PROSPERO (CRD42024550863), aimed to evaluate the efficacy and safety of HA fillers for horizontal neck lines. Comprehensive searches of Ovid MEDLINE and Embase were performed up to May 2024. Eleven studies (

Identifiers

PMID41560960
PMCPMC12813632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.