Evidence map›Paper›PMID 41560920›Full record

ReviewFrontiers in plant science2025

Plant-derived vesicles: isolation strategies and therapeutic applications.

Jiazhong Li, Zhiyi Wang, Feiran Wang, Xiuwei Du, Xiaogang Pang

Abstract readReview
In one paragraph

Review in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Advances in Research onInternational journal of molecular sciences · 2026
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  15. Inhibitory Effect ofInternational journal of nanomedicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiazhong LiShandong Technician Institute, Jinan, China.
Zhiyi WangCollege of Pharmaceutical Science, Shandong University of Traditional Chinese Medicine, Jinan, China.
Feiran WangJinan Third People's Hospital, The Third People's Hospital of Jinan, Shandong, China.
Xiuwei DuExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, China.
Xiaogang PangExperimental Center, Shandong University of Traditional Chinese Medicine, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-derived vesicles (PDVs) are vesicle-like structures secreted by plant cells, containing components such as membrane proteins、nucleic acids and enzymes. These vesicles play significant roles in plant growth, tissue repair and self-defense. Additionally, PDVs are safe and easy to extract, and they demonstrate promising therapeutic effects on inflammation, cancer and wound healing. Due to their unique properties, PDVs can serve as drug carriers, effectively shuttling through cells to aid disease treatment. In this study, we review the methods for separating and preparing PDVs and highlight their application in disease treatment using nanovesicles derived from plants such as cucumber、broccoli、lemon、turmeric、ginseng、ginger、garlic、grape、yam、tomato and grapefruit. The biomedical applications of PDVs in drug delivery, anticancer therapies, anti-inflammatory responses, antioxidation and wound healing are also introduced. Finally, the feasibility, characteristics, challenges and future prospects of PDVs are discussed.

Indexed as

drug deliverynanovesiclesplant-derived vesiclespreparation and purification of PDVstherapeutic applications

Identifiers

PMID41560920
PMCPMC12812987

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.