Evidence map›Paper›PMID 41560897›Full record

ArticleFood chemistry: X2026

Safflower oil body emulsion digestion behavior and regulation of intestinal microorganisms: The influence of polysaccharide xanthan gum.

Xinxin Lan, Chenlu Tao, Linghe Zhang, Jinnan Guo, Zhuofu Wu, Jing Li, Dinghe Wang, Jian Wei, Xiaokun Li, Jing Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinxin LanSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Chenlu TaoCollege of Life Science, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun 130118, China.
Linghe ZhangCollege of Life Science, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun 130118, China.
Jinnan GuoCollege of Life Science, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun 130118, China.
Zhuofu WuCollege of Life Science, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun 130118, China.
Jing LiCollege of Life Science, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun 130118, China.
Dinghe WangCollege of Life Science, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun 130118, China.
Jian WeiInstitute for Safflower Industry Research of Shihezi University/Pharmacy College of Shihezi University/Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Xinjiang 832003, China.
Xiaokun LiSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Jing YangInstitute for Safflower Industry Research of Shihezi University/Pharmacy College of Shihezi University/Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, Xinjiang 832003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As naturally pre-emulsified oil-in-water systems, plant-derived oil bodies are sustainable alternatives to synthetic emulsions for food and pharmaceutical applications. We developed a novel safflower oil body emulsion (SOBE) that utilizes xanthan gum polysaccharides to form hydrogen bonds with membrane proteins on the surface of oil bodies. We aimed to investigate the pH-dependent interfacial evolution and digestive fate of SOBE and analyze changes in its fatty acid composition. Furthermore, we examined the dose-dependent modulation of the gut microbiota by SOBE through 16S sequencing, predict the key metabolic pathways, including carbohydrate metabolism, amino acid biosynthesis, and membrane transport systems. We demonstrated that SOBE is a multifunctional bioactive carrier exhibiting dual functionalities-enhancing lipid digestion and modulating microbial activity. This approach effectively addresses the reduced bioavailability commonly observed in traditional oil body formulations. Our findings support the use of SOBE as a multifunctional carrier for nutritional products, functional foods, and targeted drug delivery systems.

Indexed as

Gut microbiotaInterface componentsOil body emulsionSafflower

Identifiers

PMID41560897
PMCPMC12814077

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.