Evidence map›Paper›PMID 41560895›Full record

ArticleFood chemistry: X2026

Impact of reduced pancreatin and bile on Fe and Zn bioaccessibility assessment using the INFOGEST

Alexandre Minami Fioroto, Molly Muleya, Lolita Wilson, Kaja Kristensen, Ruth Price, David A Gray, Eduardo Purgatto, Elizabeth H Bailey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandre Minami FiorotoFood Research Center (FoRC), University of São Paulo (USP), São Paulo, SP, Brazil.
Molly MuleyaSchool of Biosciences, Division of Food, Nutrition and Dietetics, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire LE12 5RD, UK.
Lolita WilsonSchool of Biosciences, Division of Agriculture and Environmental Sciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire LE12 5RD, UK.
Kaja KristensenSchool of Biosciences, Division of Food, Nutrition and Dietetics, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire LE12 5RD, UK.
Ruth PriceSchool of Biosciences, Division of Food, Nutrition and Dietetics, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire LE12 5RD, UK.
David A GraySchool of Biosciences, Division of Food, Nutrition and Dietetics, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire LE12 5RD, UK.
Eduardo PurgattoFood Research Center (FoRC), University of São Paulo (USP), São Paulo, SP, Brazil.
Elizabeth H BaileySchool of Biosciences, Division of Agriculture and Environmental Sciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire LE12 5RD, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a previously proposed stable isotope approach based on the INFOGEST protocol, pancreatin and bile amounts were reduced due to their high mineral content, which interferes with Fe and Zn measurements. The present study examined the impact of reagent reduction on macronutrient digestibility and, consequently, mineral release in ten food samples. Macronutrient digestibility was higher under INFOGEST conditions. However, Fe and Zn solubility were not consistently modified across matrices, although, a general trend of increased solubility was observed in the standard INFOGEST method. Fe solubility increased by 64-91 % in cereals, beans, and nuts but decreased by 48 % in sweet potato. Similarly, Zn solubility increased by 11-75 % in oats, nuts, and leafy vegetables, while it decreased by 18-64 % in potatoes and beans. Overall, the influence of enzymatic action and background minerals could not be isolated, thus standardisation of the INFOGEST method for mineral bioaccessibility assessment is urgently needed.

Indexed as

BileBioaccessibilityDigestibilityIn vitro digestionIsotopic labellingMineralsPancreatin

Identifiers

PMID41560895
PMCPMC12814079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.