ArticleJournal of human reproductive sciences
Changing Profile of the PCOS Women: A 15 Year Retrospective Cohort Study.
Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Dietary Antioxidant Capacity, Inflammation, and Insulin Resistance in Women with Polycystic Ovary Syndrome: An Integrated Metabolic and Nutritional Assessment.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
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Authors and funding
1 author.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting reproductive-aged women, with a global prevalence of 5%-10%, and up to 25% in certain populations. Developing countries like India have witnessed a surge in obesity and related metabolic comorbidities due to rapid urbanisation and lifestyle transitions. This study examines temporal changes in the clinical and metabolic profile of women with PCOS from Odisha, India, over the past 15 years. Aim: This study aims to analyse how PCOS women have changed in their clinical, phenotypic, biochemical and metabolic parameters over the last two decades. Settings and Design: Private hospital and retrospective analysis. Materials and Methods: This retrospective chart review included 1530 women diagnosed with PCOS (Rotterdam criteria) at a tertiary care centre in Odisha. Patients were grouped into three periods: Period 1 (2009-2013), Period 2 (2014-2018) and Period 3 (2019-2024), with approximately equal numbers. Anthropometric, biochemical and ultrasonographic features were compared across time periods. Statistical Analysis Used: The data were analysed using Chi-square and Kruskal-Wallis tests and the R v4.1.1 (R Core Team, 2021) software. Results: Mean body mass index increased from 26.40 ± 4.61 kg/m Conclusion: Over the last 15 years, the metabolic and phenotypic profile of Indian women with PCOS has worsened significantly. These findings highlight the need for early lifestyle interventions and public health strategies targeting metabolic risk factors in this population.
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