Evidence map›Paper›PMID 41560833›Full record

ArticleMaterials today. Bio2026

Pressure-sensitive composite bandages with high toughness, self-healability and strong tissues adhesion for rapid bone fixation and accelerated osteogenesis via immunomodulation and neovascularization.

Puzhou Lei, Shuya Wang, Kaiwen Chen, Linghanqing Wang, Yi Shen, Huize Zhong, Sida Chen, Xin Su, Yu Zhao, Huanan Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Puzhou LeiDepartment of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, 110004, PR China.
Shuya WangKey State Laboratory of Fine Chemicals, School of Bioengineering, Dalian University of Technology, Dalian, 116024, PR China.
Kaiwen ChenKey State Laboratory of Fine Chemicals, School of Bioengineering, Dalian University of Technology, Dalian, 116024, PR China.
Linghanqing WangDepartment of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, 110004, PR China.
Yi ShenKey State Laboratory of Fine Chemicals, School of Bioengineering, Dalian University of Technology, Dalian, 116024, PR China.
Huize ZhongKey State Laboratory of Fine Chemicals, School of Bioengineering, Dalian University of Technology, Dalian, 116024, PR China.
Sida ChenDepartment of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, 110004, PR China.
Xin SuDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100032, PR China.
Yu ZhaoDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100032, PR China.
Huanan WangKey State Laboratory of Fine Chemicals, School of Bioengineering, Dalian University of Technology, Dalian, 116024, PR China.
Lei LiDepartment of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, 110004, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone adhesives have gained considerable interest as an adjunctive approach for fragment fixation in comminuted fractures and bone graft procedures. However, the current adhesives are mostly used to fill the bone void to achieve the fixation of broken bones, which inevitably impedes regeneration at the fracture interface. To address this limitation, we present an integrated bone-adhesive bandage that enables robust adhesion to bone tissue without occluding the healing space. Precise modulation of the viscoelastic properties in a poly(octamethylene citrate)-gelatin (POC-G) copolymer facilitates strong interfacial adhesion to bone but also unique internal cohesion to enable self-heal. Further incorporation of hydroxyapatite (HA) nanoparticles significantly enhances the adhesive strength (570.43 ± 21.82 kPa) while preserving mechanical toughness (1648.66 ± 367.81 kJ m

Indexed as

bone adhesiveCitric acid-based polymerHydroxyapatiteOsteogenic compositePressure-sensitive adhesives

Identifiers

PMID41560833
PMCPMC12813315

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.