Evidence map›Paper›PMID 41560672›Full record

ReviewACS chemical biology2026

Structure-Activity Relationships of Anabaenopeptins as Carboxypeptidase and Phosphatase Inhibitors.

Megan L Quandt, Judy Westrick, Jeremy J Kodanko

Abstract readReview
In one paragraph

Review in ACS chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Megan L QuandtDepartment of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.
Judy WestrickDepartment of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.ORCID 0000-0002-1712-5737
Jeremy J KodankoDepartment of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.ORCID 0000-0001-5196-7463

Funding

Synthesis and quantitation of microcystins and anabaenopeptins in the Great Lakes region to establish human exposure risks via ingestion and inhalationR01ES034017 · NIEHS · WAYNE STATE UNIVERSITY · PI Andrew P Ault, Andrew Michael Fribley · 2023 to 2026
$2.3M
AnchorChem LLC: Pioneering Solutions to Create a Stable Supply Chain of Cyanopeptides and Cyanotoxins to Address Global Health ThreatsR41ES038414 · NIEHS · ANCHORCHEM LLC · PI KODANKO, JEREMY, SZLAG SILVA, REGINA · 2025 to 2025
$307k
NIEHS NIH HHS R01 ES034017NIEHS NIH HHS R41 ES038414
6 · The paper itself

Abstract

Anabaenopeptins are a family of cyanobacterial cyclic peptides that display potent enzyme inhibition, particularly against carboxypeptidases A and B, as well as the serine/threonine phosphatases PP1 and PP2A. Defined by a 19-membered macrocyclic ring and a ureido-linked exocyclic amino acid, these compounds vary considerably in their amino acid composition, influencing both potency and selectivity. This review compiles published IC

Indexed as

CarboxypeptidasesEnzyme InhibitorsPeptides, CyclicCyanobacteriaHumansStructure-Activity RelationshipCarboxypeptidasesEnzyme InhibitorsPeptides, Cyclic

Identifiers

PMID41560672
PMCPMC12927552

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.