Evidence map›Paper›PMID 41560495›Full record

ArticleJournal of Korean Neurosurgical Society2026

The Effect of Cranioplasty on Cerebrospinal Fluid Dynamics in the Cerebral Aqueduct.

Peiwen Yao, Zhouqi Qian, Rui Ji, Ke Wang

Abstract read
In one paragraph

Article in Journal of Korean Neurosurgical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peiwen Yao *Department of Neurosurgery, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Zhouqi Qian *Department of Neurosurgery, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Rui JiDepartment of Radiology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Ke WangDepartment of Neurosurgery, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China. kewang@tongji.edu.cn.

Funding

Shanghai Natural Science Foundation 23ZR1449300
6 · The paper itself

Abstract

objectiveThis study investigated the cerebrospinal fluid (CSF) dynamic changes before and after cranioplasty using phase-contrast cine magnetic resonance imaging.

methodsWe performed a prospective observational study in the patients who underwent cranioplasty in the neurosurgical department of our hospital between June 2022 and March 2025. We reviewed the changes of CSF flow parameters in the cerebral aqueduct before and after cranioplasty.

resultsTotally, nine patients were enrolled, including five males and four females, with a mean age of 48.1 years. The time interval between decompressive craniectomy (DC) and cranioplasty was 119.1±45.1 days. The skull defect diameter and area were 10.7±2.2 cm and 94.4±34.6 cm2, respectively. There are significant increases in forward flow volume (p=0.002), backward flow volume (p=0.002), net stroke volume (p=0.012), absolute stroke volume (p=0.001), mean flux (p=0.005), mean velocity (p=0.001), and peak velocity (p<0.001) after cranioplasty when compared with those parameters before cranioplasty. No significant correlation was observed between patient characteristics and the improvement magnitude of CSF flow parameters caused by cranioplasty.

conclusionThis study indicates that cranioplasty may have beneficial effects on CSF flow dynamics in the cerebral aqueduct after DC, which provides therapeutic potentials for complications related to CSF flow stagnancy after DC.

Indexed as

Cerebral aqueductCerebrospinal fluidCranioplastyDecompressive craniectomyMagnetic resonance imaging, phase contrast

Identifiers

PMID41560495
PMCPMC13341214

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.