Evidence map›Paper›PMID 41560283›Full record

ArticleRadiology and oncology2026

Quality of life in Slovenian patients with skull base tumours: cross-cultural adaptation and validation of a Slovenian skull base inventory.

Domen Vozel, Jure Urbancic, Saba Battelino, Nina Bozanic Urbancic, Nejc Steiner, Tomislav Felbabic, Roman Bosnjak

Abstract readValidation Study
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Article in Radiology and oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Domen VozelDepartment of Otorhinolaryngology and Cervicofacial Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Jure UrbancicDepartment of Otorhinolaryngology and Cervicofacial Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Saba BattelinoDepartment of Otorhinolaryngology and Cervicofacial Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Nina Bozanic UrbancicDepartment of Otorhinolaryngology and Cervicofacial Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Nejc SteinerManchester University NHS Foundation Trust, Wythenshawe Hospital, Southmoor Rd, Wythenshawe, Manchester, Great Britain.
Tomislav FelbabicFaculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Roman BosnjakFaculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSkull base tumours frequently manifest as severe physical morbidity and quality of life (QoL) impairment. The disease-related QoL measurement can be performed with disease specific questionnaires, e.g. Skull base inventory (SBI). PATIENTS AND

methodsThe study consisted of two parts: (1) cross-cultural adaptation and psychometric testing of the Slovenian SBI (SBI-SLO) and (2) QoL assessment in skull base tumours. Two groups completed the SBI-SLO: 1.) adult patients without prior treatment of anterior, anterolateral and/or central skull base and 2.) healthy controls. Patients with skull-base tumours were further analysed for difference in SBI-SLO total score and domain scores between 1.) benign and malignant tumours and 2.) pituitary macroadenomas and other benign tumours.

results59 patients (46% male, 54% female, median age 57.7 years) and 47 subjects from control group (49% male, 51% female, median age 42,2 years) completed SBI-SLO, which demonstrated an excellent level of internal consistency (Cronbach's alpha = 0.924) and excellent test-retest reliability (intraclass correlation coefficient [ICCA] = 0.952). The discriminant validity was confirmed (

conclusionsA skull base tumour, especially malignant, can exert a substantial detrimental effect on a patient's quality of life. The SBI is a key tool for assessing QoL, also available in Slovenian.

Indexed as

Quality of LifeSkull Base NeoplasmsAdultAgedCross-Cultural ComparisonFemaleHumansMaleMiddle AgedPsychometricsReproducibility of ResultsSloveniaSurveys and Questionnairescarcinomameningiomaneoplasmsquality of Lifeskull base

Identifiers

PMID41560283
PMCPMC13012383

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