ArticleMedicine2026
Physical activity patterns and all-cause mortality in U.S. adults with osteopenia or osteoporosis: A prospective cohort study.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study is to examine the association between physical activity patterns and all-cause mortality among U.S. adults with osteopenia or osteoporosis. Data from adults with osteopenia or osteoporosis were obtained from the National Health and Nutrition Examination Survey 2007 to 2018, a nationally representative survey of U.S. adults, with mortality follow-up through 2019. Bone mineral density was assessed at 4 femoral sites using dual-energy X-ray absorptiometry. Physical activity was self-reported and categorized as physically inactive (<150 minutes/week) or active (≥150 minutes/week). Active participants were further classified as weekend warriors (1-2 sessions/week) or regularly active (≥3 sessions/week). Cox proportional hazards models estimated hazard ratios (HRs) for all-cause mortality. Among 5522 participants (mean age: 61.74 years), 991 (17.95%) died during a mean follow-up of 85.0 months. Compared to regularly active participants, weekend warriors had no statistically significant difference in all-cause mortality risk (HR: 1.12; 95% confidence interval (CI): 0.62-2.03). Further subdivision of weekend warriors by frequency (1 vs 2 days/week) yielded similar results. In contrast, physical inactivity was associated with significantly higher mortality risk (HR: 1.78; 95% CI: 1.38-2.28). Among adults with osteopenia or osteoporosis, meeting physical activity guidelines, even over 1 or 2 days per week, was associated with lower mortality risk. These findings support the weekend warrior pattern as a viable strategy for improving longevity in this at-risk population.
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