Evidence map›Paper›PMID 41560031›Full record

SynthesisMedicine2026

Effects of exercise intervention on inhibitory control in children and adolescents with autism spectrum disorders: A systematic review and meta-analysis.

Yansen Li, Yanwei Qi, Yulin Yang, Ruijiao Zhang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yansen LiPhysical Education College of Zhoukou Normal University, Henan, China.
Yanwei QiSports Training Department of Henan Sport University, Henan, China.
Yulin YangCollege of Sports Science, Shenyang Normal University, Liaoning, China.ORCID 0009-0009-7743-7634
Ruijiao ZhangDepartment of Sports welfare Education, Woosuk University, Wanju-gun, Jeollabuk-do, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExercise interventions have a positive impact on executive functioning in children and adolescents with autism spectrum disorders (ASD), but the efficacy of inhibitory control (IC) following exercise interventions is unclear. The aim was to investigate the effects of an exercise intervention on IC function in children and adolescents with ASD and to explore the underlying mechanisms.

methodsWe searched 8 English (Web of Science, PubMed, Scopus, Embase, MEDLINE, SPORTDiscus, Cochrane Library, and APA PsycINFO) and 2 Chinese databases (China Biomedical and CNKI) up to November 2024. Two authors independently extracted data, assessed bias with Cochrane Risk of Bias 2 tool, and graded evidence with Grading of Recommendations, Assessment, Development and Evaluation. Eighteen studies were included, of which 8 entered the meta-analysis.

resultsOverall, the combined effect of exercise intervention on IC in children and adolescents with ASD was statistically significant in the intervention group compared to the control group (standardized mean difference = -0.49, 95% confidence interval [-0.72 to -0.26], Z = 4.16, P < .0001), with no heterogeneity (I2 = 0%), and no publication bias was found by funnel plots and Egger test, sensitivity analysis revealed no publication bias, and the findings were stable. Subgroup analysis revealed that, in terms of movement patterns, martial arts interventions appeared to be more effective in enhancing IC, while ball sports and combined sports did not show significant effects. Interventions with shorter session durations (≤45 minutes), more frequent weekly sessions (>2), and shorter intervention cycles (≤4 weeks) tended to demonstrate slightly better outcomes, although not all subgroup differences reached statistical significance.

conclusionsExercise interventions have a significant impact on IC in children and adolescents with ASD. Martial arts interventions may be more beneficial for improving IC in children and adolescents with ASD. Similarly, shorter sessions, higher weekly frequency, and shorter overall intervention cycles tended to yield somewhat better effects. However, given the variation in the number and quality of included studies, these findings must be further validated by more scientifically objective randomized controlled trials.

Indexed as

Autism Spectrum DisorderExercise TherapyInhibition, PsychologicalAdolescentChildExecutive FunctionHumansMaleautism spectrum disorderschildren and adolescentsinhibitory controlmeta-analysis

Identifiers

PMID41560031
PMCPMC12826300

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.