Evidence map›Paper›PMID 41559997›Full record

ArticleMedicine2026

Delayed motherhood: Birth outcomes at extremely advanced maternal age: A retrospective cohort study.

Alaattin Karabulut, Sercan Kantarci, Uğurcan Dağli, Elif Atici, Alper İleri, Defne Engür, Özgün Uygur, Volkan Karataşli

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alaattin KarabulutDepartment of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital, Bornova, Izmir, Turkey.ORCID 0000-0002-0244-4401
Sercan KantarciDepartment of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital, Bornova, Izmir, Turkey.ORCID 0000-0001-5608-060
Uğurcan DağliDepartment of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital, Bornova, Izmir, Turkey.ORCID 0009-0006-3015-0909
Elif AticiDepartment of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital, Bornova, Izmir, Turkey.ORCID 0009-0003-4836-7063
Alper İleriDepartment of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital, Bornova, Izmir, Turkey.ORCID 0000-0002-4713-5805
Defne EngürDepartment of Neonatology, University of Health Sciences Tepecik Training and Research Hospital, Izmir, Turkey.ORCID 0000-0003-0405-085
Özgün UygurDepartment of Neonatology, University of Health Sciences Tepecik Training and Research Hospital, Izmir, Turkey.ORCID 0000-0002-7580-915
Volkan KarataşliDepartment of Gynecologic Oncology, Balikesir Atatürk City Hospital, Balikesir, Turkey.ORCID 0000-0002-4015-6494

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate and compare pregnancy and neonatal outcomes in women aged ≥ 45 years, categorized as having extremely advanced maternal age (EAMA), and a control group of women aged 25 to 35 years who delivered within the same time period. A retrospective cohort study was conducted at a tertiary referral center in Turkey, including 143 women aged ≥ 45 and 250 women aged 25 to 35 who gave birth between January 2017 and January 2024. Obstetric and neonatal outcomes were compared, including gestational age, mode of delivery, birthweight, Apgar scores, and neonatal intensive care unit (NICU) admissions. Cesarean delivery (71.3% vs 47.6%, P < .001), preterm birth (21.0% vs 9.2%, P = .001), and NICU admissions (21.7% vs 12.8%, P = .02) were significantly more frequent in the EAMA group. The median birthweight was also significantly lower in this group (3000 g vs 3305 g; P < .001), and extremely preterm births (<28 weeks) occurred only in the EAMA group. Women aged ≥ 45 years face significantly higher risks of adverse obstetric and neonatal outcomes, underscoring the need for tailored prenatal care and delivery planning in this growing patient population as delayed motherhood becomes increasingly prevalent.

Indexed as

Maternal AgePregnancy OutcomeAdultAdvanced Maternal AgeApgar ScoreBirth WeightCesarean SectionDelivery, ObstetricFemaleGestational AgeHumansInfant, NewbornIntensive Care Units, NeonatalMiddle AgedPregnancyPremature Birthadvanced maternal agecesarean deliveryneonatal outcomesperinatal complications

Identifiers

PMID41559997
PMCPMC12826323

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.