Evidence map›Paper›PMID 41559989›Full record

ArticleMedicine2026

Application of patient blood management protocol to reduce transfusion rates in limb salvage operations for osteosarcoma: A retrospective study.

Jong Hoon Park, Hyun Min Lee, Yeok Gu Hwang

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jong Hoon ParkDepartment of Orthopedic Surgery, Korea University Anam Hospital, Koera University College of Medicine, Seoul, Republic of Korea.
Hyun Min LeeDepartment of Orthopedic Surgery, Korea University Anam Hospital, Koera University College of Medicine, Seoul, Republic of Korea.
Yeok Gu HwangDepartment of Orthopedic Surgery, Ewha Womans University Seoul Hospital, Ewha University College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncologic orthopedic surgery stands as one of the primary causes necessitating blood transfusions. In an endeavor to mitigate transfusion requirements, the implementation of patient blood management (PBM) holds significant value. We undertook a retrospective study to juxtapose pre and post-PBM implementation scenarios in the context of treating osteosarcoma through limb salvage surgery in patients' extremities. This study encompasses 25 patients who underwent surgery between 2008 and 2016 at our institution, with a comparison drawn between cases before and after PBM adoption. Parameters such as transfusion rate (TR), transfusion volume (TV), and complications were subjected to analysis for both strategies. The PBM group exhibited notably reduced TR and TV compared to the control group (P < .01). PBM-associated complications primarily included anemia, reduction in hematocrit levels, and limited declines in hemodynamic status, which were generally mild and well-tolerated. In the control group, surgical site infections were observed in 13.3% of patients. When contrasted with the control group, the implementation of PBM in surgical interventions for osteosarcoma limb salvage procedures demonstrates its effectiveness in significantly reducing blood TRs.

Indexed as

Blood TransfusionBone NeoplasmsLimb SalvageOsteosarcomaAdolescentAdultChildFemaleHumansMaleRetrospective StudiesYoung Adultallogeneic blood transfusionblood managementosteosarcomatransfusion

Identifiers

PMID41559989
PMCPMC12826304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.