Evidence map›Paper›PMID 41559891›Full record

ReviewAsian spine journal2026

Comparison of biportal versus uniportal endoscopic decompression for the treatment of lumbar degenerative disease: a systematic review and meta‑analysis.

Alexander Yu, Mark Kurapatti, Ryan Hoang, James Hong, Nancy Shrestha, Ryan Stadler, Peter Campbell, Junho Song, Joshua Lee, Samuel K Cho

Abstract readReview
In one paragraph

Review in Asian spine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexander YuDepartment of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mark KurapattiDepartment of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ryan HoangDepartment of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
James HongDepartment of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nancy ShresthaChicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Ryan StadlerRutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Peter CampbellDepartment of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Junho SongDepartment of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Joshua LeeDepartment of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Samuel K ChoDepartment of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA. samuel.cho@mountsinai.org.

Funding

CerapedicsGlobus Medical
6 · The paper itself

Abstract

STUDY

designSystematic review and meta-analysis. PURPOSE: To perform a comprehensive meta-analysis comparing clinical outcomes of uniportal versus biportal endoscopic spine surgery across decompression procedures in patients with lumbar degenerative disease (LDD). OVERVIEW OF LITERATURE: Uniportal endoscopic spine surgery has been a widely adopted minimally invasive technique, whereas biportal endoscopy has recently emerged as a promising alternative with potential advantages in surgical outcomes.

methodsA systematic review and meta-analysis of comparative studies was conducted in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. PubMed, Embase, and Scopus databases were searched to identify relevant studies. Eleven studies encompassing 374 uniportal and 368 biportal patients were included. Outcomes analyzed were Oswestry Disability Index (ODI), Visual Analog Scale (VAS) scores for back and leg pain, complication rates, operative time, and length of hospital stay.

resultsBiportal endoscopic surgery was associated with a significantly lower ODI at 1-3 months and at final follow-up compared with uniportal surgery. However, uniportal discectomy demonstrated significantly shorter operative time and length of hospital stay than biportal discectomy. No significant differences were observed between approaches in terms of VAS scores, complication rates, or ODI at other time points.

conclusionsBoth uniportal and biportal endoscopic spine surgeries yield comparable postoperative outcomes in LDD. Although biportal surgery showed a modest advantage in ODI improvement, it did not reach the minimal clinically important difference. Uniportal surgery demonstrated greater efficiency in terms of operative time and recovery, particularly for discectomy procedures.

Indexed as

EndoscopyIntervertebral disc degenerationLumbar regionMinimally invasive surgical proceduresSpinal decompression

Identifiers

PMID41559891
PMCPMC13329259

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.