Evidence map›Paper›PMID 41559807›Full record

ReviewLaboratory animal research2026

MPOX transmission risks and biosafety protocols in laboratory animal research.

Mobolaji Abdulateef Ayoola, Abayomi Oyeyemi Ajagbe, Blessing Simon Oyeleye, Christiana Ololade Olajimbiti, Maryam Ebunoluwa Zakariya, Al-Hassan Soliman Wadan, Ifukibot Levi Usende

Abstract readReview
In one paragraph

Review in Laboratory animal research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mobolaji Abdulateef AyoolaDepartment of Veterinary Anatomy, University of Abuja, Abuja, Nigeria.
Abayomi Oyeyemi AjagbeDepartment of Anatomy, Nile University of Nigeria, Abuja, Nigeria.
Blessing Simon OyeleyeDepartment of Veterinary Pathology, University of Abuja, Abuja, Nigeria.
Christiana Ololade OlajimbitiDepartment of Veterinary Pathology, University of Abuja, Abuja, Nigeria.
Maryam Ebunoluwa ZakariyaDepartment of Veterinary Public Health, Faculty of Veterinary Medicine, University of Ilorin, Ilorin, Nigeria.
Al-Hassan Soliman WadanOral Biology Department, Faculty of Dentistry, Galala University, Galala, Egypt.
Ifukibot Levi UsendeDepartment of Veterinary Anatomy, University of Abuja, Abuja, Nigeria. Ifukibot.usende@uniabuja.edu.ng.ORCID http://orcid.org/0000-0002-3894-1426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mpox, known before now as monkeypox, is a novel zoonotic disease that may infect both humans and animals. It usually spreads by direct contact with bodily fluids, lesion material, or fomites (such as contaminated linens) and prolonged face-to-face contact. Mpox can spread to laboratory animals in a research laboratory through either a general outbreak or during procedures. Animal models are essential as we learn more about how infections occur and how to treat illnesses in both humans and animals which require laboratory procedures with mpox virus. As drug-resistant organisms proliferate, bioterrorism becomes a greater danger, international trade and travel expand, and the number of newly developing infectious illnesses grows, the use of animals in infectious disease research has increased. Animal research offers a solid basis for clinical trials used in standard medication development. Animal studies must be planned to produce conclusive effectiveness evidence that is robust, rigorous, and repeatable per the animal rule so that the agency may depend on the results when making regulatory decisions. There is a need to understand the transmission risk and biosafety protocol to be in place in laboratory settings to prevent an outbreak and probably contain an outbreak. Hence, this review discussed the overview of mpox in animal research, biosafety protocols in mpox research, laboratory waste management methods, legal and ethical considerations in mpox research, challenges in carrying out mpox research and future directions.

Indexed as

Animal researchBiosafety levelBiosafety protocolLaboratory animalMonkeypox

Identifiers

PMID41559807
PMCPMC12821299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.