Evidence map›Paper›PMID 41559705›Full record

SynthesisBMC musculoskeletal disorders2026

Whole-body vibration training and bone mineral density in older adults: an updated systematic review and meta-analysis.

Wendi Chen, Xingyi Li, Changzhou Chen

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wendi ChenSchool of Physical Education, Shanghai University of Sport, Shanghai, China.
Xingyi LiDepartment of Sport and Health, Shinhan University, Uijeongbu-si, Gyeonggi Province, Republic of Korea.
Changzhou ChenSchool of Physical Education, Shanghai University of Sport, Shanghai, China. chenchangzhou@sus.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the effects of whole-body vibration training on bone mineral density at different sites in the elderly population via meta-analysis.

methodsWe systematically searched CNKI, VIP, Wanfang, China Biomedical Literature Database, PubMed, Cochrane Library, Embase, and Web of Science from inception to April 20, 2025, for randomized controlled trials comparing whole-body vibration training with conventional exercise on bone mineral density in elderly individuals. Methodological quality was assessed using the TESTEX (Tool for the Assessment of Study Quality and Reporting in Exercise) checklist, while risk of bias was evaluated with the Cochrane RoB 2.0 tool. Data were analyzed using Review Manager 5.4 for meta-analysis and heterogeneity assessment, Stata MP 18 for Egger’s test, and the GRADE framework for evidence quality evaluation.

resultsFourteen studies involving 1,447 participants were included, with TESTEX = 9.5 (good quality) and risk of bias (21% low risk, and 79% some concerns). Results indicated that whole-body vibration training significantly increased bone mineral density in the Ward's triangle region (WMD=0.04, P < 0.00001) and greater trochanter region (WMD = 0.03, P = 0.0002) in the elderly. It also showed improvement effects on the femoral neck region (WMD = 0.01, P = 0.01) and lumbar spine L2‒L4 region (WMD = 0.04, P = 0.003). However, no significant effects were observed in the lumbar spine L1‒L4 region (WMD=0.00, P=0.79) or total hip region (WMD=0.01, P=0.56).

conclusionsWhole-body vibration training significantly increased bone mineral density in Ward's triangle and greater trochanter regions in elderly subjects, with smaller improvements in the femoral neck region. The L2‒L4 lumbar spine segment may substantially increase, whereas the L1‒L4 lumbar spine segment and total hip region have negligible effect.

trial registrationCRD420251038478.

Indexed as

Bone DensityOsteoporosisVibrationAgedFemur NeckHumansRandomized Controlled Trials as TopicBone mineral densityElderlyMeta-analysisWhole-body vibration training

Identifiers

PMID41559705
PMCPMC12908257

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.