ArticleBMC medical imaging2026
Impact of slice thickness on CACS calculation with virtual non-contrast in photon-counting CT.
Article in BMC medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThis study aims to investigate the feasibility of coronary artery calcium scoring (CACS) calculating from PureCalcium virtual non-iodine algorithm on photon-counting detector CT (PCD-CT) and the potential impact of different section thickness, level of virtual monoenergetic images (VMIs), and quantum iterative reconstruction (QIR) on the accuracy of CACS quantification. MATERIALS AND
methodsA total of 123 patients who underwent coronary CT angiography on PCD-CT with a separate true non-contrast CACS (CACS
resultsAt all investigated section thickness, VMI, and QIR levels, the CACS
conclusionCACS derived from the PureCalcium algorithm with optimized reconstruction parameters shows excellent correlation with true non-contrast scans derived values. Thus, it is may possible to use the PureCalcium virtual non-iodine algorithm to replace the true non-contrast scans for CACS quantification, without additional radiation dose exposure.
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