Evidence map›Paper›PMID 41559536›Full record

ArticleNano letters2026

Mapping Optical Chirality with Single Fluorescent Molecules.

Daniel Marx, Ivan Gligonov, David Malsbenden, Dominik Wöll, Oleksii Nevskyi, Jörg Enderlein

Abstract read
In one paragraph

Article in Nano letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel MarxIII. Institute of Physics-Biophysics, Georg August University, 37077 Göttingen, Germany.
Ivan GligonovIII. Institute of Physics-Biophysics, Georg August University, 37077 Göttingen, Germany.
David MalsbendenInstitute of Physical Chemistry, RWTH Aachen University, 52074 Aachen, Germany.
Dominik WöllInstitute of Physical Chemistry, RWTH Aachen University, 52074 Aachen, Germany.ORCID 0000-0001-5700-4182
Oleksii NevskyiIII. Institute of Physics-Biophysics, Georg August University, 37077 Göttingen, Germany.ORCID 0000-0003-2893-481X
Jörg EnderleinIII. Institute of Physics-Biophysics, Georg August University, 37077 Göttingen, Germany.ORCID 0000-0001-5091-7157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single fluorescent molecules, acting as ideal point dipoles, offer a unique means to probe light-matter interactions at the nanoscale. Here, we exploit this property to map the chiral and vectorial structure of tightly focused optical fields using individual, immobilized terrylene diimide molecules. By scanning the excitation focus under linear and circular polarization, we obtain three-dimensional fluorescence excitation maps that directly visualize the handedness and symmetry breaking inherent to circularly polarized light. The measured patterns show excellent quantitative agreement with a full vectorial diffraction model, enabling the accurate determination of both molecular orientations and the local field structure. This approach establishes single molecules as quantitative nanoprobes of optical chirality, offering new strategies for characterizing complex light fields and polarization effects in nanophotonic, plasmonic, and anisotropic materials.

Indexed as

light−matter interactionnanophotonicsoptical chiralitypolarization microscopysingle-molecule fluorescencevectorial light fields

Identifiers

PMID41559536
PMCPMC12983358

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.