Evidence map›Paper›PMID 41559408›Full record

ArticleScientific reports2026

Analysis of the spatial-temporal distribution and functional morphology of telocytes in goat testes.

Jiasen Feng, Chunyuan Dai, Qi Wang, Imran Tarique, Zhaoxuan Zhu, Yisheng Wang, Xinzi Guo, Ping Yang

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PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Jiasen FengMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Chunyuan DaiMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Qi WangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Imran TariqueDepartment of Biomedicine, Atta-Ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Pakistan.
Zhaoxuan ZhuMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Yisheng WangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Xinzi GuoMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Ping YangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China. yangping@njau.edu.cn.

Funding

National Key Research and Development Program of China No. 2024YFD1800404
6 · The paper itself

Abstract

Telocytes (TCs), a distinct interstitial cell population, are increasingly being reported in the male reproductive system. This study aimed to confirm TC presence in goat testes, to characterize their immunophenotype and age-related differences. Testes from one-, two-, and twelve-month-old goats were examined by using transmission electron microscopy (TEM) and double immunofluorescence (DIF) staining. TEM revealed that TCs were widely distributed among peritubular myoid cells (PMC) in testes from 12-month-old goats and exhibited reduced cell bodies and cytoplasm compared to TCs in juvenile goats. Their telopodes (TPs) displayed the characteristic bead-like structure of alternating podomers (Pms) and podoms (Pds). The telopodes were slender and curved, intertwining near collagen bundles and blood vessels and releasing abundant vesicles. DIF staining reliably identified goat testicular TCs as CD34+/vimentin+ cells with elongated processes and spindle- or triangular-shaped bodies. TCs in 12-month-old goats were significantly longer than those in juvenile goats and had more elongated nuclei. They also exhibited markedly more protrusions and were arranged in four or five parallel stromal layers. The DIF findings corroborated the TEM observations. This study provides evidence of age-related morphological and distributional changes in goat testicular TCs, establishing a foundation for understanding their role in maintaining the microenvironmental homeostasis of the testes.

Indexed as

TelocytesTestisAnimalsAntigens, CD34GoatsMaleMicroscopy, Electron, TransmissionTelopodesVimentinAntigens, CD34VimentinGoat testisImmunophenotypeTelocytesTransmission electron microscopy

Identifiers

PMID41559408
PMCPMC12894951

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.