Evidence map›Paper›PMID 41559369›Full record

ArticleScientific reports2026

Nationwide genomic surveillance of carbapenem- and colistin-resistant Klebsiella pneumoniae bloodstream isolates in Thailand (2020-2024).

Kulsumpun Krobanan, Watcharaporn Kamjumphol, Phimrata Leethongdee, Aekkawat Unahalekhaka, Orapan Sripichai, Nattapong Cheunban, Nalumon Thadtapong, Chattip Kurehong, Pilailuk Akkapaiboon Okada, Jiraphan Premsuriya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kulsumpun KrobananNational Antimicrobial Resistance Surveillance Center, Thailand (NARST), National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand.
Watcharaporn KamjumpholNational Antimicrobial Resistance Surveillance Center, Thailand (NARST), National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand.
Phimrata LeethongdeeNational Antimicrobial Resistance Surveillance Center, Thailand (NARST), National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand.
Aekkawat UnahalekhakaNational Antimicrobial Resistance Surveillance Center, Thailand (NARST), National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand.
Orapan SripichaiNational Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand.
Nattapong CheunbanNational Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand.
Nalumon ThadtapongNational Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand.
Chattip KurehongNational Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand.
Pilailuk Akkapaiboon OkadaNational Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, 11000, Thailand.
Jiraphan PremsuriyaPrincess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy, Bangkok, 10210, Thailand. Jiraphan.pre@cra.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Klebsiella pneumoniae is a major cause of bloodstream infections worldwide and is increasingly associated with multidrug resistance, particularly to carbapenems and colistin, which severely limits treatment options. This study investigated the genomic epidemiology of K. pneumoniae bloodstream infection (BSI) isolates collected in Thailand between 2020 and 2024. A total of 227 K. pneumoniae BSI isolates collected nationwide through the National Antimicrobial Resistance Surveillance Center, Thailand were subjected to antimicrobial susceptibility testing and whole-genome sequencing, followed by multilocus sequence typing, AMR gene detection, plasmid profiling, virulence scoring, phylogenetic analysis, and genotype-phenotype correlation. Among the isolates, 199 were resistant to carbapenems, seven were resistant only to colistin, and 21 were not resistant to either carbapenems or colistin. Three high-risk sequence types (ST) (ST16, ST147, and ST231) predominated in most regions, whereas the south showed greater clonal diversity. ST16 isolates commonly co-harbored bla

Indexed as

CarbapenemsColistinDrug Resistance, Multiple, BacterialKlebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial AgentsHumansMicrobial Sensitivity TestsMultilocus Sequence TypingPhylogenyThailandWhole Genome SequencingAnti-Bacterial AgentsCarbapenemsColistinAntimicrobial resistance surveillanceBloodstream infectionsCarbapenem-resistant Klebsiella pneumoniaeColistin-resistant Klebsiella pneumoniaeThailand

Identifiers

PMID41559369
PMCPMC12894937

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.