Evidence map›Paper›PMID 41559320›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Metachronous nasopharyngeal carcinoma following sinonasal inverted papilloma - a diagnostic enigma.

Deviprasad Dosemane, Meera Niranjan Khadilkar, Nithya Chandy, Divya Subramanian, Nayana Rao, Susana Iqbal

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Deviprasad DosemaneDepartment of Otorhinolaryngology - Head and Neck, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.
Meera Niranjan KhadilkarDepartment of Otorhinolaryngology - Head and Neck, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India. meera.khadilkar@manipal.edu.ORCID http://orcid.org/0000-0002-2006-8913
Nithya ChandyDepartment of Otorhinolaryngology - Head and Neck, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.
Divya SubramanianDepartment of Otorhinolaryngology - Head and Neck, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.
Nayana RaoDepartment of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.
Susana IqbalDepartment of Otorhinolaryngology - Head and Neck, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInverted papilloma (IP) is a benign Schneiderian epithelial tumour with a well-recognized potential for recurrence and malignant transformation, most commonly to squamous cell carcinoma (SCC). Carcinoma arising in the nasopharynx after prior IP is exceedingly rare, and distinguishing malignant conversion from a metachronous nasopharyngeal carcinoma (NPC) poses a diagnostic challenge. CASE REPORT: We report a rare, interesting case of a nasopharyngeal lesion with histopathological features of non-keratinizing SCC in a patient previously treated surgically for sinonasal IP.

conclusionDifferentiating malignant transformation of IP from a metachronous malignancy is complex. In this case, the short interval between diagnoses, anatomical separation, and absence of Schneiderian features favour interpretation as a metachronous NPC, highlighting the importance of continued surveillance and prompt evaluation of new symptoms in patients treated for IP.

Indexed as

Carcinoma, Squamous CellNasopharyngeal CarcinomaNasopharyngeal NeoplasmsNeoplasms, Second PrimaryPapilloma, InvertedParanasal Sinus NeoplasmsDiagnosis, DifferentialHumansMaleMiddle AgedHuman papilloma virusInverted papillomaNasopharyngeal carcinomaNasopharyngeal neoplasmsSinonasal tractSquamous cell carcinoma

Identifiers

PMID41559320
PMCPMC13053405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.