Evidence map›Paper›PMID 41558726›Full record

ArticleAnalytical chemistry2026

From Home to Transcriptome: Comparing the Transcriptomic Profile of Induced Immune Response via Lipopolysaccharide Stimulation in homeRNA and Venous Blood.

Lauren G Brown, Xiaofu Wei, Laura A Milton, M Yunos Alizai, James W MacDonald, Theo K Bammler, Yuting Zeng, Ingrid Robertson, Karen N Adams, Yi-Chin Toh and 4 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Lauren G BrownDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-5932-2691
Xiaofu WeiDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Laura A MiltonDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
M Yunos AlizaiDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0009-0001-5370-1252
James W MacDonaldDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.
Theo K BammlerDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.
Yuting ZengDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Ingrid RobertsonDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Karen N AdamsDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Yi-Chin TohSchool of Mechanical, Medical and Process Engineering, Queensland University of Technology, Brisbane, Queensland 4001, Australia.ORCID 0000-0002-4105-4852
Damien ChaussabelComputer Sciences Department, The Jackson Laboratory, Farmington, Connecticut 06032, United States.
Erwin BerthierDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-4421-9034
Amanda J HaackDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Ashleigh B ThebergeDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.ORCID 0000-0002-3394-1435

Funding

Theberge Admin Supp Undergraduate Summer Research ExperiencesR35GM128648 · NIGMS · UNIVERSITY OF WASHINGTON · PI Ashleigh Brooks Theberge · 2018 to 2026
$4.7M
NIGMS NIH HHS R35 GM128648
6 · The paper itself

Abstract

Remote blood sampling offers multiple advantages over traditional clinic-based blood sampling studies, including greater patient inclusion, more frequent sampling, and broader geographical reach. Combining remote blood sampling with transcriptomic analysis opens potential in translational applications for capturing acute and dynamic immune responses to various exposures. In this study, we establish the feasibility of homeRNA, a capillary blood collection and RNA

Indexed as

Gene Expression ProfilingLipopolysaccharidesRNATranscriptomeCytokinesHumansCytokinesLipopolysaccharidesRNA

Identifiers

PMID41558726
PMCPMC12998979

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.