Evidence map›Paper›PMID 41558678›Full record

ArticleJournal of primary care & community health

Development and Evaluation of an AI Avatar Educational Tool for Depression and Anxiety: A Qualitative Pilot Study.

Adam Bleik, Patricia Marr, Shelly-Anne Li, Debbie Kwan, Catherine Ji, Kori Leblanc, Yuki Meng, Christine Papoushek

Abstract read
In one paragraph

Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adam BleikUniversity Health Network, Department of Pharmacy, Toronto, Ontario, Canada.ORCID 0009-0009-6173-0713
Patricia MarrUniversity Health Network, Department of Pharmacy, Toronto, Ontario, Canada.ORCID 0009-0004-2719-6768
Shelly-Anne LiUniversity Health Network, Toronto Western Family Health Team, Toronto, Ontario, Canada.ORCID 0000-0002-0189-0880
Debbie KwanUniversity Health Network, Department of Pharmacy, Toronto, Ontario, Canada.ORCID 0009-0009-1649-8222
Catherine JiUniversity Health Network, Toronto Western Family Health Team, Toronto, Ontario, Canada.ORCID 0000-0001-7544-6005
Kori LeblancUniversity Health Network, Department of Pharmacy, Toronto, Ontario, Canada.ORCID 0000-0002-9996-0663
Yuki MengUniversity of British Columbia, Faculty of Pharmaceutical Sciences, Vancouver, British Columbia, Canada.ORCID 0000-0002-0486-2447
Christine PapoushekUniversity Health Network, Department of Pharmacy, Toronto, Ontario, Canada.ORCID 0000-0002-3531-0696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression and anxiety affect nearly 1 in 4 Canadians. Traditional patient education materials, such as handouts, are often lengthy and difficult to understand, leading to disengagement. Human-like artificial intelligence (AI) avatars offer a novel way to supplement education by delivering consistent, engaging video content that mimics human interaction and is easily accessible online.

objectiveThis pilot study aimed to develop a human-like, non-generative AI avatar educational video to support education on antidepressants for patients living with depression and anxiety. The secondary objectives were to evaluate participants perceptions of the tool across 3 domains: credibility, satisfaction, and understanding.

methodsThe video was developed through 2 Plan-Do-Study-Act (PDSA) cycles, informed by prior research on patient-reported barriers and enablers to antidepressant use. After viewing the video, participants completed a survey assessing the 3 domains. Success was predefined as ≥60% of participants rating each domain ≥4 on a 5-point Likert scale. Open-ended feedback was summarized descriptively to help inform revisions.

resultsFifteen University Health Network (UHN) Patient Partners participated in PDSA Cycle 1, most with lived experience of depression or anxiety and high digital literacy. Success thresholds were achieved for credibility (75%) and satisfaction (67%) but not for understanding (50%). After revisions, 10 participants from the original group completed PDSA Cycle 2, where all domains exceeded thresholds (credibility 90%, satisfaction 85%, understanding 82%). Participants described the tool as trustworthy, clear, and engaging.

conclusionThis pilot study demonstrated that human-like, non-generative AI avatars can be an effective supplementary educational tool to deliver education on antidepressants for individuals with depression and anxiety. The tool demonstrated acceptability across credibility, satisfaction, and perceived understanding, highlighting its potential to enhance patient engagement and access to reliable information. As a scalable and adaptable format, avatar-based education may extend beyond mental health to other conditions, languages, and clinical settings. Future studies should examine its impact on knowledge retention, treatment adherence, and integration into clinical practice.

Indexed as

Antidepressive AgentsAnxietyArtificial IntelligenceAvatarDepressionPatient Education as TopicAdultFemaleHumansMaleMiddle AgedPatient SatisfactionPilot ProjectsQualitative ResearchAntidepressive Agentsanxietyartificial intelligence in primary carebehavioral healthdepressionhealth literacymood disorderpharmacyprimary carequalitative methodsquality improvement

Identifiers

PMID41558678
PMCPMC12819983

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.