Evidence map›Paper›PMID 41558211›Full record

ArticleEnvironment international2026

Prenatal greenness, air pollution, and birthweight: Assessing sensitive windows of exposure and sub-populations in a multi-exposure setting.

Melissa Fiffer, Mercedes A Bravo, Dominique Zephyr, Joshua L Tootoo, Charlotte Roscoe, Grete Wilt, Rafiga Gasymova, Peter James, Marie Lynn Miranda

Abstract read
In one paragraph

Article in Environment international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Melissa FifferChildren's Environmental Health Initiative, University of Illinois Chicago, Chicago, IL, USA. Electronic address: mfiffe2@uic.edu.
Mercedes A BravoGlobal Health Institute, School of Medicine, Duke University, Durham, NC, USA.
Dominique ZephyrChildren's Environmental Health Initiative, University of Illinois Chicago, Chicago, IL, USA.
Joshua L TootooChildren's Environmental Health Initiative, University of Illinois Chicago, Chicago, IL, USA.
Charlotte RoscoeEnvironmental Systems and Human Health, Oregon Health & Science University-Portland State University School of Public Health, Portland, OR, USA; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Grete WiltDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Rafiga GasymovaChildren's Environmental Health Initiative, University of Illinois Chicago, Chicago, IL, USA.
Peter JamesDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Public Health Sciences, University of California, Davis School of Medicine, CA, USA.
Marie Lynn MirandaChildren's Environmental Health Initiative, University of Illinois Chicago, Chicago, IL, USA; Department of Pediatrics, University of Illinois Chicago, Chicago, IL, USA.

Funding

Research Project: Evaluating Green Infrastructure Impacts on Climate Change Related Heat, Air Quality, Flooding, and Cardiopulmonary Outcomes in ChicagoP20MD019989 · NIMHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MALECKI, KRISTEN MARY CHOSSEK · 2024 to 2024
$3.9M
Bringing Modern Data Science Tools to Bear on Environmental Mixtures: Administrative Supplement for U3 PopulationsR01ES028819 · NIEHS · UNIVERSITY OF NOTRE DAME · PI MIRANDA, MARIE LYNN · 2018 to 2021
$2.4M
Disparate Exposures, Disparate Outcomes: The Effect of Cumulative DisadvantageR00MD011304 · NIMHD · RESEARCH TRIANGLE INSTITUTE · PI BRAVO, MERCEDES AURELIA · 2019 to 2021
$722k
NIEHS NIH HHS R01 ES028819NIMHD NIH HHS P20 MD019989NIMHD NIH HHS R00 MD011304
6 · The paper itself

Abstract

introductionStudies show that prenatal neighborhood greenness is positively associated with birthweight. However, few go beyond a pregnancy-long greenness average or consider air pollution co-exposures. We used time-varying greenness and air pollution estimates to explore sensitive windows and subpopulations.

methodsWe examined Michigan (U.S.) birth records between 2007 and 2016 (n = 798,071). We derived the Normalized Difference Vegetation Index (NDVI) from Landsat images (30 m

resultsIn adjusted models, an IQR (0.2 unit) increase in NDVI within a 270 m buffer was associated with a 12.3 g (95% CI: 9.7 g, 15.0 g) higher birthweight. Positive associations were observed in all trimesters, and across all maternal education and neighborhood median household income levels. PM

conclusionsBirthweight is positively associated with residential greenness in all trimesters after co-adjusting for air pollutants. Addresses surrounded by the least greenness had the strongest inverse PM

Indexed as

Air PollutionBirth WeightMaternal ExposureAir PollutantsFemaleHumansMichiganParticulate MatterPregnancyResidence CharacteristicsAir PollutantsParticulate MatterAir pollutionBirth outcomesBirthweightGreennessMultiple exposuresSensitive windows

Identifiers

PMID41558211
PMCPMC13361753

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.