Evidence map›Paper›PMID 41557850›Full record

ReviewInterdisciplinary cardiovascular and thoracic surgery2026

Surgical Explant of Degenerated Transcatheter Valves: A New Type of Threat?

Giuseppe Verolino, Michele Di Mauro, Martin Czerny, Michal Kawczynski, Samuel Heuts, Elham Bidar, Roberto Lorusso

Abstract readReview
In one paragraph

Review in Interdisciplinary cardiovascular and thoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giuseppe VerolinoCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht 6229 HX, The Netherlands.ORCID 0000-0002-2369-109X
Michele Di MauroCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht 6229 HX, The Netherlands.ORCID 0000-0003-2611-5626
Martin CzernyDepartment of Cardio-Vascular Surgery, University Hospital, Freiburg, 79106, Germany.ORCID 0000-0003-4766-9775
Michal KawczynskiCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht 6229 HX, The Netherlands.ORCID 0000-0003-2628-9562
Samuel HeutsCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht 6229 HX, The Netherlands.
Elham BidarCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht 6229 HX, The Netherlands.ORCID 0000-0002-9569-4900
Roberto LorussoCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht 6229 HX, The Netherlands.ORCID 0000-0002-1777-2045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTranscatheter treatment for valvular heart diseases has markedly expanded its indications due to reduced invasiveness and hospitalization time. Despite favourable results, several peculiar and more frequent shortcomings than occur with a surgical-based implant have been reported. This review provides the currently available information regarding a transcatheter heart valve (THV) implant and reoperation, focusing on recent available data about surgical management strategies for THV degeneration.

methodsFor this narrative review, we searched Medline through the end of March 2025 using medical subject headings and text words supplemented by scanning the bibliographies of recovered articles. The terms "transcatheter valve degeneration," "TAVI degeneration," "surgical treatment," and "surgical explant" have been combined using the Boolean operator "AND".

resultsCurrently available articles focus specifically on the aortic THV explant. Peculiar intraoperative (like coronary ostium, aortic wall and annular injury due to THV explant) or short-term postoperative complications related to THV explant have been reported. Thirty-day mortality has been shown to range between 12% and 32.6%, and only short and heterogeneous follow-up periods are available to date. A careful work-up to indicate that the valve-in-valve procedure is not feasible or not appropriate when facing degenerated THV and a cautious, detailed plan of the surgical explant have been recently recommended.

conclusionsTHV explants due to valve degeneration are rapidly increasing, but, due to the related risk for intra- and post-procedural complications, careful preoperative evaluation and intraoperative handling are warranted.

Indexed as

Aortic ValveDevice RemovalHeart Valve DiseasesHeart Valve ProsthesisProsthesis FailureTranscatheter Aortic Valve ReplacementHumansPostoperative ComplicationsReoperationbiological mitral valvebioprosthetic valve failurestructural valve degenerationTHV explanttranscatheter aortic valve implantationtranscatheter heart valve

Identifiers

PMID41557850
PMCPMC12872939

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.