Evidence map›Paper›PMID 41557467›Full record

ArticleeLife2026

ATAD2 mediates chromatin-bound histone chaperone turnover.

Ariadni Liakopoulou, Fayçal Boussouar, Daniel Perazza, Sophie Barral, Emeline Lambert, Tao Wang, Florent Chuffart, Ekaterina Bourova-Flin, Charlyne Gard, Denis Puthier and 4 more

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ariadni LiakopoulouUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0009-0005-8964-9205
Fayçal BoussouarUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0003-4529-4893
Daniel PerazzaUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0002-7703-4984
Sophie BarralUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0001-9915-6096
Emeline LambertUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0009-0005-6909-5831
Tao WangUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0002-5178-6969
Florent ChuffartUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0001-6064-5183
Ekaterina Bourova-FlinUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0002-5673-9045
Charlyne GardAix-Marseille Université, Marseille, France.
Denis PuthierAix-Marseille Université, Marseille, France.ORCID https://orcid.org/0000-0002-7240-5280
Sophie RousseauxUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0001-5246-5350
Christophe ArnoultUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0002-3753-5901
André VerdelUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0001-6048-3794
Saadi KhochbinUniversité Grenoble Alpes, INSERM U1209, CNRS UMR 5309, Institute for Advanced Biosciences, Grenoble, France.ORCID https://orcid.org/0000-0002-0455-0857

Funding

Agence Nationale de la Recherche ANR EpiSperm 4 (ANR-19-CE12- 0014)Agence Nationale de la Recherche ANR Episperm 5 (ANR-23-CE12-0028)Agence Nationale de la Recherche ANR NME-CoA (ANR-23-CE14-0050)
6 · The paper itself

Abstract

ATAD2, a conserved protein which is predominantly expressed in embryonic stem (ES) cells and spermatogenic cells, emerges as a crucial regulator of chromatin plasticity. Our previous parallel studies conducted in both ES cells and

Indexed as

ATPases Associated with Diverse Cellular ActivitiesChromatinDNA-Binding ProteinsHistone ChaperonesHistonesAnimalsCell Cycle ProteinsMaleMiceProtein BindingSpermatogenesisSpermatozoaTranscription FactorsTranscription, GeneticATPases Associated with Diverse Cellular ActivitiesCell Cycle ProteinsChromatinDNA-Binding ProteinsHira protein, mouseHistone ChaperonesHistonesTranscription FactorsAtad2chaperone turnoverchromatin dynamicschromosomesgene expressionmouseSpermatogenesis

Identifiers

PMID41557467
PMCPMC12818868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.