Evidence map›Paper›PMID 41557230›Full record

ReviewSub-cellular biochemistry2026

Structural Biology of Actin: Interplay Between Molecular Assembly, Conformational Polymorphism and ATPase.

Yuichiro Maéda, Toshiro Oda, Akihiro Narita, Yusuke Kanematsu, Mitsusada Iwasa, Shuichi Takeda

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sub-cellular biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuichiro MaédaGraduate School of Informatics, Nagoya University, Nagoya, Japan. ymaeda@cc.nagoya-u.ac.jp.
Toshiro OdaFaculty of Health and Welfare, Tokai Gakuin University, Gifu, Japan.
Akihiro NaritaGraduate School of Science, Nagoya University, Nagoya, Japan.
Yusuke KanematsuGraduate School of Advanced Science and Engineering, Hiroshima University, Hiroshima, Japan.
Mitsusada IwasaGraduate School of Science, Nagoya University, Nagoya, Japan.
Shuichi TakedaGraduate School of Informatics, Nagoya University, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Actin was first identified as a major muscle protein with two key activities: polymerization and ATPase. Although the significance of these activities in muscle contraction was unclear, subsequent cell biological studies revealed that actin is abundant also in non-muscle cells, where it drives dynamic remodeling through ATP-dependent treadmilling. Biochemical studies revealed that the polymerization coupled with ATP hydrolysis produces two distinct F-actin states: a stable ADP-P

Indexed as

ActinsAdenosine TriphosphatasesAdenosine DiphosphateAdenosine TriphosphateAnimalsHumansHydrolysisModels, MolecularProtein ConformationActinsAdenosine DiphosphateAdenosine TriphosphatasesAdenosine TriphosphateActin treadmillingATP hydrolysisConformational transitionCryo-EMCrystallographyDomain motionFiber diffractionPi releaseQM/MM

Identifiers

PMID41557230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.