Evidence map›Paper›PMID 41557121›Full record

ArticleEJNMMI physics2026

Evaluation of precalculated attenuation correction map for preclinical cardiac PET/MR using a

Hanan Rida, Mona Guetlin, Mikael Naveau, Martin Haas, Alexandre Lebrun, Michael Joubert, Alain Manrique

Abstract read
In one paragraph

Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Hanan RidaCyceron UR4650 PSIR, Université Caen Normandie, GIP Cyceron, Campus Jules Horowitz, bvd Henri Becquerel, BP 5229, 14074, Caen, France.
Mona GuetlinCyceron UR4650 PSIR, Université Caen Normandie, GIP Cyceron, Campus Jules Horowitz, bvd Henri Becquerel, BP 5229, 14074, Caen, France.
Mikael NaveauUAR3408/US50 Cyceron, CNRS, INSERM, Université Caen Normandie, Caen, France.
Martin HaasPreclinical Imaging Division, Bruker BioSpin, Ettlingen, Germany.
Alexandre LebrunCyceron UR4650 PSIR, Université Caen Normandie, GIP Cyceron, Campus Jules Horowitz, bvd Henri Becquerel, BP 5229, 14074, Caen, France.
Michael JoubertCyceron UR4650 PSIR, Université Caen Normandie, GIP Cyceron, Campus Jules Horowitz, bvd Henri Becquerel, BP 5229, 14074, Caen, France.
Alain ManriqueCyceron UR4650 PSIR, Université Caen Normandie, GIP Cyceron, Campus Jules Horowitz, bvd Henri Becquerel, BP 5229, 14074, Caen, France. manrique@cyceron.fr.ORCID http://orcid.org/0000-0002-1578-0922

Funding

GCS G4 FHU CARNAVALRégion Normandie RIN SoGlu PET-MR
6 · The paper itself

Abstract

backgroundIn preclinical PET/MR, attenuation correction (AC) uses a mix of pre-calculated attenuation maps accounting for animal cradles and organ segmentation obtained from whole-body MR using a volume coil. The development of X-nuclei such as MATERIALS AND

methodsWe developed a 3D-printed cradle (DC) embedding a 20 mm surface coil made of PLA (polylactic acid), coated with a thin cap of epoxy. An attenuation map was generated using computed tomography and integrated into PET reconstruction. To validate AC, we compared PET images to those obtained using a conventional cradle and a volume coil (CC). Various image quality metrics were evaluated in various phantoms including a NEMA NU-4 (recovery coefficients (RC), uniformity (%STD), spillover ratio (SOR)), a homogenous phantom (slice and inter-slice uniformity) and a resolution phantom (spatial resolution). Finally, cardiac

resultsRC obtained using DC and CC configurations were not significantly different. However, the %STD was significantly increased with the DC (5.07 ± 0.18) vs. CC (3.29 ± 0.53, p = 0.0002) leading to a decreased CNR with DC. The SOR was similar between the two cradles. In homogenous phantom, there was a non-significant 1.58% underestimation of the PET signal near the surface coil and 5% overestimation on the opposite side when using the DC vs. CC. Uniformity between slice was significantly higher in DC than in CC (3.15 ± 1.2% for DC vs. 2.24 ± 0.7% for CC, p = 0.02) while uniformity inter-slice was similar in DC and CC (2.25 ± 0.83% for DC vs. 1.93 ± 0.44% for CC, p = 0.2). Spatial resolution was similar between DC and CC (axial: 1.80 vs. 1.63 mm, tangential: 1.62 vs. 1.79 mm and radial resolution: 1.53 vs. 1.76 mm for DC and CC respectively). In-vivo, cardiac standardized uptake values were similar between the two cradles (3.55 ± 0.89 and 3.59 ± 1.02 for DC and CC respectively, p = 0.81).

conclusionPre-calculated attenuation map using a standardized positioning of MR surface coil provided similar

Indexed as

attenuation correctionPET-MRpreclinicalsodium MRI

Identifiers

PMID41557121
PMCPMC12901769

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.