ArticleUrology practice2026
Real-World Utility of Cxbladder Triage for Patients with Microhematuria: A Matched Cohort Study.
Article in Urology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
purposeWe sought to evaluate the real-world utility of adding the Cxbladder Triage test to microhematuria diagnostic workflow in an integrated health care system.
methodsWe conducted a retrospective matched cohort study of patients with microhematuria tested with Cxbladder Triage, a urine-based biomarker of mRNA targets and clinical factors to assess urothelial cancer risk. We matched untested controls based on age, encounter date, and Hematuria Risk Index score. The cohort was stratified by Cxbladder Triage result: low probability (<4.00, cystoscopy could be deferred) vs physician-directed protocol (≥4.00, cystoscopy recommended). We evaluated the use of cystoscopy, CT urograms, and new diagnoses of bladder cancer.
resultsWe matched 3353 patients tested with Cxbladder Triage with 3353 controls according to AUA risk (15.7% AUA low risk for cases and controls,
conclusionsCxbladder Triage testing decreases burden of cystoscopy and CT urogram use among patients with microhematuria. This test maintains similar cancer detection overall and among patients with microhematuria at greater risk for underlying malignancy.
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