Evidence map›Paper›PMID 41556877›Full record

ArticleThe Journal of infectious diseases2026

Risk-Based Prophylactic Human Papillomavirus Vaccination of Heterosexual US Men Aged 27 to 45 Years for Prevention of Oropharyngeal Cancer.

Anil K Chaturvedi, Gregory W Haber, Barry I Graubard, Li C Cheung, Maura L Gillison, Rebecca Landy

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anil K ChaturvediDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Gregory W HaberInformation Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland, USA.
Barry I GraubardDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Li C CheungDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.
Maura L GillisonDepartment of Thoracic/Head and Neck Medical Oncology, Division of Cancer Medicine, MD Anderson Cancer Center, Houston, Texas, USA.
Rebecca LandyDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.ORCID 0000-0003-4042-4820

Funding

Cancer Prevention and Research Institute of TexasNIHUS National Cancer Institute
6 · The paper itself

Abstract

Human papillomavirus (HPV) vaccination of US individuals aged 27-45 years is recommended through shared clinical decision-making. To enable shared decision-making, we used a microsimulation-based state-transition model to develop and validate a risk-prediction model to identify heterosexual men aged 27-45 years at high-risk of acquiring oral HPV-16 infections. A risk model for incident oral HPV-16 infections had good discrimination (AUC = 0.73) and calibration (ratio of expected to the observed number of incident oral HPV-16 infections through age 45 years [E/O] = 1.01) in internal cross-validation. Compared to vaccinating all men aged 27-45, vaccinating 44% of men with highest model-predicted risk would prevent 80% of incident oral HPV-16 infections through age 45 years and reduce the number needed to be vaccinated to prevent 1 infection by 45% (184 vs 100).

Indexed as

Oropharyngeal NeoplasmsPapillomavirus InfectionsPapillomavirus VaccinesVaccinationAdultHeterosexualityHuman papillomavirus 16HumansMaleMiddle AgedRisk AssessmentUnited StatesPapillomavirus VaccinesHPVHuman papillomavirusoropharyngeal cancerrisk stratificationvaccination

Identifiers

PMID41556877
PMCPMC13271403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.