Evidence map›Paper›PMID 41556866›Full record

ArticleJournal of the American College of Cardiology2026

Environmental Stressors and Cardiovascular Health: Acting Locally for Global Impact in a Changing World: A Statement of the European Society of Cardiology, the American College of Cardiology, the American Heart Association, and the World Heart Federation.

Thomas Münzel, Thomas Lüscher, Christopher M Kramer, Keith Churchwell, Amam Mbakwem, Sanjay Rajagopalan

Abstract readConsensus Statement
In one paragraph

Article in Journal of the American College of Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thomas MünzelDepartment of Cardiology, University Medical Center Mainz, Johannes Gutenberg University, Langenbeckstrasse 1, 55131 Mainz, Germany; German Center for Cardiovascular Research, DZHK, Partner Site Rhine-Main, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany. Electronic address: tmuenzel@uni-mainz.de.
Thomas LüscherHeart Division, Cardiovascular Academic Group, Royal Brompton and Harefield Hospitals, King's College, London SW3 6NP, United Kingdom; Center for Molecular Cardiology, University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland; European Society of Cardiology, 2035 route des colles, 80179 Biot, 06903 Sophia Antipolis, France.
Christopher M KramerCardiovascular Division, Department of Medicine, University of Virginia Health System, 1215 Lee St, Charlottesville, Virginia 22908-0158, USA; American College of Cardiology, 2400 N St NW, Washington, DC 20037, USA.
Keith ChurchwellYale School of Medicine, 333 Cedar St, New Haven, Connecticut 06510, USA; American Heart Association, 7272 Greenville Avenue, Dallas, Texas 75231-5129, USA.
Amam MbakwemDepartment of Medicine, College of Medicine, University of Lagos, Lagos 100245, Lagos, Nigeria; World Heart Federation, 32, rue de Malatrex, 1201 Geneva, Switzerland.
Sanjay RajagopalanHarrington Heart and Vascular Institute, University Hospitals, 11100 Euclid Avenue, Cleveland, Ohio 44106, USA; Case Western Reserve University, School of Medicine, 10900 Euclid Ave., Cleveland, Ohio 44106-4990, USA. Electronic address: sanjay.rajagopalan@case.edu.

Funding

Diversity Suppplement (CIRCADIAN) Circadian Disruption as Mediator of Cardiometabolic Risk in Air PollutionR35ES031702 · NIEHS · CASE WESTERN RESERVE UNIVERSITY · PI Sanjay Rajagopalan · 2021 to 2026
$5.9M
NIEHS NIH HHS R35 ES031702
6 · The paper itself

Abstract

Non-communicable diseases (NCDs) account for 70% of global mortality and are responsible for over 38 million deaths annually, with cardiovascular disease (CVD) constituting most of these fatalities. While traditional risk factors for CVD have long been recognized, there is growing evidence that a rising prevalence of ubiquitous environmental risk factors (ERFs) may play an increasingly significant role in the genesis and rising prevalence of NCDs. ERFs include many interconnected anthropogenic exposures with cumulative compound health impacts, including air pollution, noise exposure, artificial light at night, plastic pollution, chemical pollution and the various effects of climate change, such as heat extremes, desert storms, floods and wildfires. Urbanization has intensified the impact of many ERFs and created intense exposure environments, highlighting the urgency and the opportunity to address these for maximum public health benefit. Impactful intervention often requires regulatory and policy-driven efforts addressing the genesis of exposures and minimizes their health impact, particularly in vulnerable populations who may contribute the least but may be impacted the most. Solutions must involve the development of resiliency and adaptation measures to a changing world, where the probability of sudden catastrophic and cascading events is much more likely. Political will and international cooperation are essential in establishing and enforcing regulations that promote cleaner air and water, quieter and natural biodiverse environments, and sustainable infrastructure in urban, and rural medical facilities. Integration of planetary and environmental health into cardiovascular care will be vital in reducing the burden of NCDs globally. By addressing the root causes of environmental stressors, it is possible to reduce the incidence of CVDs and promote healthier, just and sustainable societies.

Indexed as

American Heart AssociationCardiologyCardiovascular DiseasesEnvironmental ExposureGlobal HealthSocieties, MedicalClimate ChangeEuropeHumansRisk FactorsUnited Statesair pollutioncardiovascular diseaseclimate changeenvironmental stressorsmitigationnoisepublic health awareness

Identifiers

PMID41556866
PMCPMC13160175

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.