ArticlemBio2026
Molecular insights into polyurethane biodegradation in
Lucie Semenec, Ram Maharjan, Vaheesan Rajabal, Aidan P Tay, Xin Xu, Hannah Lott, Fiona S B Facey, Hue Dinh, Sasha G Tetu, Thomas C Williams and 2 more
Abstract read
In one paragraphArticle in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
12 authors.
Lucie Semenec *ARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.
Ram Maharjan *ARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID 0000-0002-1514-6681 Vaheesan RajabalARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.
Aidan P TayARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.
Xin XuARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.
Hannah LottARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.
Fiona S B FaceyARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID 0009-0009-6062-795X Hue DinhARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.
Sasha G TetuARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID 0000-0002-8943-3499 Thomas C WilliamsARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.
Ian T PaulsenARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID 0000-0001-9015-9418 Amy K CainARC Centre of Excellence in Synthetic Biology, Department of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID 0000-0002-4230-6572 Funding
ARC Future Fellowship FT220100152US Department of Defense FA520921P160US Department of Defense W911NF2320155
6 · The paper itselfAbstract
Global accumulation of difficult-to-recycle plastics, including polyurethane (PU), poses a significant environmental threat, as current recycling strategies are insufficient to meet the growing demand. IMPORTANCE: The polyurethane (PU) market is projected to reach $94 billion USD by 2028 and spans many industries, including automotive, construction, medical, furniture, and fashion. However, less than 30% of PU plastics are recycled, with the remainder going to landfill. The inherent recalcitrant nature of PU makes it challenging to study naturally occurring routes of PU degradation, like microbial biodegradation and its underlying genetic mechanisms. To address this, we developed a high-throughput screening method using transposon-directed insertion site sequencing (TraDIS) on the known PU-degrading strain
Indexed as
PolyurethanesPseudomonasBacterial ProteinsBiodegradation, EnvironmentalDNA Transposable ElementsGene Expression Regulation, BacterialMutagenesis, InsertionalBacterial ProteinsDNA Transposable ElementsPolyurethanesFenton reactionfunctional genomicsgacSoxidative stressplastic degradationpyoverdine
Identifiers
PMID41556818
PMCPMC12892942
What OpenQuestion holds
Textmetadata
LicenceCC BY
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