Evidence map›Paper›PMID 41556741›Full record

ReviewVeterinary medicine and science2026

Diagnosis of Paralytic Rabies by Metagenomics Next-Generation Sequencing: A Case Report and Review of the Literature.

Lianghai Cao, Xingyu Wang, Youlian Zhou, Jun Qiu, Qianlv Zeng, Chaogui Zhang, Lingai Pan

Abstract readCase ReportsReview
In one paragraph

Review in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lianghai CaoDepartment of Intensive Care Medicine, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu, Sichuan Province, China.
Xingyu WangDepartment of Intensive Care Medicine, the Second People's Hospital of Yibin, West China Hospital, Yibin, China.
Youlian ZhouDepartment of Intensive Care Medicine, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu, Sichuan Province, China.ORCID https://orcid.org/0009-0000-5065-5740
Jun QiuDepartment of Intensive Care Medicine, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu, Sichuan Province, China.
Qianlv ZengDepartment of Intensive Care Medicine, the Second People's Hospital of Yibin, West China Hospital, Yibin, China.
Chaogui ZhangDepartment of Intensive Care Medicine, the Second People's Hospital of Yibin, West China Hospital, Yibin, China.
Lingai PanDepartment of Intensive Care Medicine, Sichuan Provincial People's Hospital, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paralytic rabies is an atypical form of the disease that is notoriously difficult to diagnose early due to the absence of classic features like hydrophobia. The case being discussed presents a patient who has altered mental status, for whom the initial diagnosis was difficult due to an absent clear bite history and typical symptoms. The final diagnosis of the case was confirmed by metagenomic next-generation sequencing (mNGS) of directly from cerebrospinal fluid, which led to the detection of the rabies virus. This case underscores the critical diagnostic value of mNGS in identifying elusive neurotropic infections.

Indexed as

Dog DiseasesRabiesRabies virusAnimalsDogsHigh-Throughput Nucleotide SequencingMetagenomicscerebrospinal fluidmNGSparalytic rabiesrabies virus

Identifiers

PMID41556741
PMCPMC12817918

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.