Evidence map›Paper›PMID 41556656›Full record

ArticlemSphere2026

Zinc-enhanced activity of an antimicrobial halogenated phenazine against

Jessica K Kajfasz, Hannah B Hosay, Qiwen Gao, Robert W Huigens, José A Lemos

Abstract read
In one paragraph

Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Genomic instability and biofilm determinants inbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jessica K KajfaszDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0001-8977-8449
Hannah B HosayDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.
Qiwen GaoDepartment of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, USA.
Robert W HuigensDepartment of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia, USA.ORCID 0000-0003-3811-2721
José A LemosDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0003-0791-5863

Funding

Mechanisms of Metal Ion Homeostasis of Oral StreptococciR01DE032555 · NIDCR · UNIVERSITY OF FLORIDA · PI Jose A Lemos · 2023 to 2026
$1.8M
NIDCR NIH HHS DE032555NIDCR NIH HHS R01 DE032555NIGMS NIH HHS GM153272
6 · The paper itself

Abstract

Halogenated phenazine (HP) compounds have shown promise as antimicrobial agents, particularly against biofilm-associated Gram-positive pathogens. Among these compounds, HP-29 demonstrates potent activity against methicillin-resistant

Indexed as

Anti-Bacterial AgentsGram-Positive BacteriaPhenazinesStreptococcus mutansZincBiofilmsDrug SynergismEnterococcus faecalisIronMicrobial Sensitivity TestsAnti-Bacterial AgentsIronPhenazinesZincdental carieshalogenated phenazineS. mutanstrace metalzinc

Identifiers

PMID41556656
PMCPMC12931261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.