Evidence map›Paper›PMID 41556562›Full record

ArticleFEMS microbiology reviews2026

Limitations and safety aspects related to the use of bacteriophages in food production.

Angelika Roth, Charles M A P Franz, Stefan Hertwig, Thomas Holzhauser, Christian Hertel, Hans-Ulrich Humpf, Karl-Heinz Engel, Uwe Schwarzenbolz, Oliver Schlüter, Henry Jäger and 2 more

Abstract read
In one paragraph

Article in FEMS microbiology reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Angelika RothLeibniz Research Centre for Working Environment and Human Factors (IfADo), D-44139 Dortmund, Germany.ORCID 0000-0001-7914-2148
Charles M A P FranzMax Rubner-Institut (MRI), D-24103 Kiel, Germany.
Stefan HertwigGerman Federal Institute for Risk Assessment (BfR), D-10589 Berlin, Germany.
Thomas HolzhauserDivision of Allergology, Paul-Ehrlich-Institut (PEI), D-63225 Langen, Germany.
Christian HertelDIL German Institute of Food Technologies e.V., D-49610 Quakenbrück, Germany.
Hans-Ulrich HumpfInstitute of Food Chemistry, University of Münster, D-48140 Münster, Germany.
Karl-Heinz EngelTechnical University of Munich (TUM), D-85350 Freising, Germany.
Uwe SchwarzenbolzTechnische Universität Dresden (TUD), D-01062 Dresden, Germany.
Oliver SchlüterLeibniz Institute for Agricultural Engineering and Bioeconomy (ATB), D-14469 Potsdam, Germany.
Henry JägerUniversity of Natural Resources and Life Sciences (BOKU), AT-1180 Wien, Austria.
Kemal AganovicDIL German Institute of Food Technologies e.V., D-49610 Quakenbrück, Germany.
Volker HeinzDIL German Institute of Food Technologies e.V., D-49610 Quakenbrück, Germany.

Funding

German Research Foundation HE 2509/15-12
6 · The paper itself

Abstract

Bacteriophages are considered to have great potential as naturally occurring, antimicrobial agents for use in food production. Phages are ubiquitous in nature and can be isolated from almost all habitats. This review outlines the possibilities, as well as the limitations of their use in food production. Applications of phages in the food sector are described and the limitations of their use, as well as potential risks, are discussed. Approaches for a possible classification as either processing aid or food additive are considered, and the current status of their use in and outside the EU is presented. Finally, the need for research to close identified knowledge gaps is highlighted.

Indexed as

Bacteriophagesbiocontrolbiopreservationfood productionfood safetyphage cocktails

Identifiers

PMID41556562
PMCPMC12940142

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.