Evidence map›Paper›PMID 41556464›Full record

ArticleThe clinical respiratory journal2026

Predicting Significant Blood Pressure Reduction Through Ambulatory Blood Pressure Monitoring in Patients With Obstructive Sleep Apnea Treated With Continuous Positive Airway Pressure.

Yuanni Jiao, Hehe Zhang, Hao Wu, Xin Xi, Shuang Li, Jiang Xie

Abstract read
In one paragraph

Article in The clinical respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuanni JiaoDepartment of Respiratory and Critical Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Hehe ZhangDepartment of Respiratory and Critical Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Hao WuBeijing Anzhen Hospital Centre for Sleep Medicine and Science, Capital Medical University, Beijing, China.
Xin XiBeijing Anzhen Hospital Centre for Sleep Medicine and Science, Capital Medical University, Beijing, China.
Shuang LiDepartment of Respiratory and Critical Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jiang XieDepartment of Respiratory and Critical Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Funding

National Natural Science Foundation of China 82270099
6 · The paper itself

Abstract

objectiveContinuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) results in a modest reduction in blood pressure. This study aimed to identify parameters from 24-h ambulatory blood pressure monitoring (ABPM) that are predictive of treatment response.

methodsTreatment-naïve patients with OSA were prospectively recruited from the Centre for Sleep Medicine and Science at Beijing Anzhen Hospital between July 2023 and April 2025. All participants underwent 24-h ABPM assessments before and after 3-month CPAP therapy. Correlations between the baseline ABPM data and post-CPAP changes in blood pressure were analyzed. Multivariate analysis was used to determine whether specific baseline blood pressure cutoffs independently predicted a clinically significant reduction in blood pressure.

resultsGood CPAP adherence (median usage: 6.1 h/night and 6.0 days/week; residual apnea-hypopnea index: 1.7 events/h) was achieved among 51 recruited patients (92.2% male, median age 40.5 years). After 3 months of CPAP treatment, significant reductions were observed in nearly all blood pressure measurements. Baseline 24-h mean arterial pressure (MAP) was positively correlated with the reduction in all 24-h blood pressure measures, all nighttime blood pressure measures, and daytime MAP. Compared with patients with 24-h MAP < 96 mmHg, those with baseline 24-h MAP ≥ 96 mmHg experienced relatively high absolute and relative reductions in all blood pressure measures.

conclusionsBaseline 24-h MAP effectively predicts blood pressure reduction following CPAP therapy in patients with OSA, demonstrating the clinical value of an ABPM-guided strategy for managing patients with comorbid OSA and hypertension.

trial registrationChiCTR2300067728.

Indexed as

Blood PressureBlood Pressure Monitoring, AmbulatoryContinuous Positive Airway PressureHypertensionSleep Apnea, ObstructiveAdultFemaleHumansMaleMiddle AgedPatient CompliancePolysomnographyPredictive Value of TestsProspective StudiesTreatment Outcomeambulatory blood pressure monitoringblood pressurecontinuous positive airway pressureobstructive sleep apnea

Identifiers

PMID41556464
PMCPMC12817275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.