Evidence map›Paper›PMID 41556379›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Photothermal-Immunomodulatory Hydrogel Reinforced by Ti

Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. NIR-Assisted Multimodal Strategies for Enhanced Antibacterial Therapy.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiang ShiDepartment of orthopaedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, P. R. China.
Renliang ZhaoOrthopedics Research Institute, Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, P. R. China.
Jia WangDepartment of orthopaedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, P. R. China.
Zhenchen XiongOrthopedics Research Institute, Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, P. R. China.
Xiangtian DengOrthopedics Research Institute, Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, P. R. China.
Cheng ZhengNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, P. R. China.
Wenzhi ZhangDepartment of orthopaedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, P. R. China.ORCID https://orcid.org/0009-0008-9782-4503

Funding

Anhui Provincial Higher Education Scientific Research Project 2024AH040262New Medicine of University of Science and Technology of China YD9110002020Research Funds of the Centre for Leading Medicine and Advanced Technologies of IHM 2023IHM01071
6 · The paper itself

Abstract

MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis-conditions for which existing clinical interventions offer only limited efficacy. The utility of broad-spectrum antibiotics has become increasingly compromised by escalating drug resistance, inadequate tissue targeting, and deleterious side effects. Neutrophil extracellular traps (NETs) have emerged as a compelling immunotherapeutic avenue for eradicating multidrug-resistant pathogens. Inspired by the bactericidal and immunoregulatory functions of NETs, we developed a photothermal-immunomodulatory hydrogel reinforced by a Ti

Indexed as

HydrogelsMethicillin-Resistant Staphylococcus aureusPhotothermal TherapyStaphylococcal InfectionsWound HealingAnimalsAnti-Bacterial AgentsExtracellular TrapsHumansNanoparticlesRatsTitaniumAnti-Bacterial AgentsHydrogelsTitaniumbiomimetic NETshydrogelimmune regulationMRSAphotothermal therapy

Identifiers

PMID41556379
PMCPMC13042765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.