Evidence map›Paper›PMID 41556163›Full record

ArticleInternational journal of surgery (London, England)2026

Global scientific trends in organoids from 2000 to 2024: a data-driven bibliometric and visualized analysis.

Min Zhao, Haoxin Guo, Liangju Kuang, Junshi Dai, Xindan Cao, Kaiqi Yu, Yupeng Wang, Zhongqing Wang, Cheng Peng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of surgery (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Min ZhaoDepartment of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Key Lens Research Laboratory of Liaoning Province, Shenyang City, Liaoning Province, PR China.
Haoxin GuoDepartment of Health Data Science, School of Health Management, China Medical University, Shenyang, China.
Liangju KuangDepartment of Ophthalmology, Schepens Eye Research Institute of Mass Eye and Ear, Havard Medical School, Boston, MA, USA.
Junshi DaiDepartment of Ophthalmology, Xinqiao Hospital, Army Medical University, Chongqing, China.
Xindan CaoDepartment of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Key Lens Research Laboratory of Liaoning Province, Shenyang City, Liaoning Province, PR China.
Kaiqi YuDepartment of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Key Lens Research Laboratory of Liaoning Province, Shenyang City, Liaoning Province, PR China.
Yupeng WangDepartment of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Key Lens Research Laboratory of Liaoning Province, Shenyang City, Liaoning Province, PR China.
Zhongqing WangDepartment of Information Center, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Cheng PengDepartment of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Key Lens Research Laboratory of Liaoning Province, Shenyang City, Liaoning Province, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOrganoid technology has achieved a series of pivotal breakthroughs in the early 21st century, driving innovation across life sciences and medicine, and contributing significantly to advancements in human health and medical technologies. This cross-sectional bibliometric analysis aims to examine the development of organoid research from 2000 to 2024.

methodsLiterature data were collected on 6 December 2024 and downloaded in plain text from the Science Citation Index Expanded database. Comprehensive bibliometric mapping and analysis were performed using VOSviewer to visualize research networks and thematic developments.

resultsIn this study, 16 158 organoid publications were retrieved from the SCIE database. There were only 100 organoid studies in 2000, and from 2015 onward, the number of annual publications on this topic began to proliferate, reaching 11 747 from 2019 to 2024, accounting for 72.70% of the total number of publications. The United States ranked first worldwide in both the number of publications and total citations. Among the leading institutions, Harvard University and the University of Washington were among the most prolific. Hans Clevers collaborated with 230 prolific authors and has the most publications. With the use of organoids in cancer modeling, drug screening, and regenerative medicine, organoid technology has attracted much attention in biomedical research, and the significant increase in the number of published papers and citations signifies the expanding influence and global collaboration in the field of organoid research.

conclusionThis study contributes to the understanding of current trends and potential future advances by identifying five distinct clusters in the field.

Indexed as

bibliometriccancerchiporganoidstem-cell

Identifiers

PMID41556163
PMCPMC13105668

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.