Evidence map›Paper›PMID 41556091›Full record

ArticleCytopathology : official journal of the British Society for Clinical Cytology2026

Unusual Cytology Features of A DICER1-Mutated Thyroid Nodule: Raising Awareness of A Potential Diagnostic Pitfall During Fine Needle Aspiration.

Wenli Dai, Eduardo V Zambrano, Sabri Yilmaz, Qian Wang

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In one paragraph

Article in Cytopathology : official journal of the British Society for Clinical Cytology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Wenli DaiDepartment of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Eduardo V ZambranoDepartment of Pathology and Laboratory Medicine, Phoenix Children's Hospital, Phoenix, Arizona, USA.ORCID 0000-0002-2697-8758
Sabri YilmazSchool of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Qian WangSchool of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-4487-9726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DICER1-mutated thyroid lesions can range from indolent to aggressive neoplasms. Infarction has been recently described as a histologic feature of DICER1-mutated thyroid nodules. In this case report, we presented a DICER1-mutated nodule which presented predominantly with debris in the fine needle aspiration (FNA) specimen and was confirmed on surgical resection to be a near total infarcted nodule. To the best of our knowledge, this is the first cytopathology report of a DICER1-mutated thyroid lesion presenting as an infarcted nodule. Awareness of the features described herein may help prevent both overdiagnosis and underdiagnosis in the evaluation of thyroid nodules via FNA.

Indexed as

DEAD-box RNA HelicasesRibonuclease IIIThyroid NeoplasmsThyroid NoduleBiopsy, Fine-NeedleCytodiagnosisFemaleHumansMutationThyroid GlandDEAD-box RNA HelicasesDICER1 protein, humanRibonuclease IIIDICER1FNAinfarctionthyroid

Identifiers

PMID41556091
PMCPMC13059543

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.