Evidence map›Paper›PMID 41556029›Full record

ArticleCureus2025

Enhancing Well-Being in Cancer Survivors Through Acceptance and Commitment Therapy: A Randomized Clinical Trial.

Antonios Bozas, Anna Nisyraiou, Maria Vasilopoulou, Konstantina Stavrogianni, Marianna Zacharia, Maria Karekla, Mara Gkioka, Christina Karamanidou

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonios BozasInstitute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, GRC.
Anna NisyraiouInstitute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, GRC.
Maria VasilopoulouInstitute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, GRC.
Konstantina StavrogianniInstitute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, GRC.
Marianna ZachariaACThealthy Laboratory, Department of Psychology, University of Cyprus, Nicosia, CYP.
Maria KareklaACThealthy Laboratory, Department of Psychology, University of Cyprus, Nicosia, CYP.
Mara GkiokaInstitute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, GRC.
Christina KaramanidouInstitute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCancer affects not only physical health but also leads to considerable psychological difficulties for patients. A subset of survivors' experiences post-traumatic growth (PTG), reflecting positive psychological changes following trauma. Despite increasing interest, the mechanisms and interventions that enhance PTG are not well understood. This randomized controlled trial (RCT) aims to evaluate the efficacy of an Acceptance and Commitment Therapy (ACT)-based group intervention in fostering PTG in cancer patients diagnosed with breast, head and neck, or colorectal cancer across major oncology centers in northern Greece. METHODOLOGY: In addition to PTG, the trial assesses related psychological and physiological factors, including anxiety, depression, illness perception, spiritual well-being, and stress-related biomarkers, to explore the potential mechanisms and broader outcomes of ACT. The study will utilize a parallel-group design, comparing the ACT intervention with standard care. Participants, that is, patients who have completed their oncological therapy, will be randomized and engaged in six weeks of group sessions, with outcomes assessed through standardized questionnaires (Post-traumatic Growth Inventory (PTGI), Functional Assessment of Chronic Illness Therapy-Spiritual Well-being (FACIT-Sp), Impact of Event Scale-Revised (IES-R), Hospital Anxiety and Depression Scale (HADS)), measuring post-traumatic growth, clinical symptoms, spirituality, and biomarkers. The protocol was developed in accordance with the SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2025 guidelines. DISCUSSION: By examining the impact of the ACT-based intervention, this study seeks to elucidate the therapeutic approaches that can foster PTG, ultimately enhancing empowerment in cancer survivors. The findings will contribute to the growing body of literature on PTG, informing clinical practice and the development of evidence-based interventions.

Indexed as

actcancer survivorshippost-traumatic growthpsychological flexibilitypsycho-oncologyrandomized controlled trial

Identifiers

PMID41556029
PMCPMC12812385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.