ArticleCureus2025
Synovial Lipomatosis of the Knee: A Case Report and Review of the Literature.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Synovial lipomatosis (lipoma arborescens) is a rare, benign, intra-articular lesion characterized by villous proliferation of mature adipocytes, most commonly affecting the knee. Early recognition is essential to prevent misdiagnosis and long-term joint dysfunction. MRI is highly suggestive, while histopathology confirms the diagnosis. We describe the case of a 34-year-old male with persistent left knee monoarthritis. Laboratory investigations, including complete blood count, erythrocyte sedimentation rate, and C-reactive protein, were within normal limits. MRI showed frond-like synovial projections with fat-signal intensity suppressed on fat-saturated sequences. Histopathology confirmed the diagnosis of synovial lipomatosis. The patient underwent synovectomy, resulting in full resolution of symptoms and no recurrence during four months of follow-up. Synovial lipomatosis should be considered in patients with chronic knee effusion. MRI is usually diagnostic, and early arthroscopic synovectomy restores function, prevents degenerative changes, and achieves excellent outcomes.
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