ArticleCureus2025
Progressive Weakness in Adulthood: Lipid Storage Myopathy With Suspected Sertraline-Associated Etiology.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lipid storage myopathies (LSMs) are uncommon metabolic disorders that are not always considered during routine evaluations for weakness. We describe a 51-year-old woman with progressive proximal weakness. The patient's initial studies included electromyography (EMG), spine imaging, and serologies, all of which were unrevealing. A muscle biopsy revealed lipid accumulation, and genetic testing suggested a deficiency in multiple acyl-CoA dehydrogenase (MADD) or a defect in the riboflavin transporter. Riboflavin supplementation was recommended, and a sertraline taper was initiated after concern that prolonged selective serotonin reuptake inhibitor (SSRI) exposure might be contributing to her mitochondrial dysfunction. This case demonstrates the importance of considering metabolic myopathies in patients with unexplained progressive weakness, particularly when conventional diagnostics are inconclusive.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.