Evidence map›Paper›PMID 41555790›Full record

ArticleJournal of cosmetic dermatology2026

Complications of Dermal Injectables-A Retrospective Study.

Lynhda Nguyen, Stefan W Schneider, Ute Siemann-Harms, Katharina Herberger

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Complications of Dermal Injectables-A Retrospective Study.Journal of cosmetic dermatology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lynhda NguyenDepartment of Laser and Aesthetics, Department of Dermatology and Venereology, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany.ORCID https://orcid.org/0000-0002-1258-6390
Stefan W SchneiderDepartment of Dermatology and Venereology, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany.ORCID https://orcid.org/0000-0002-4679-7137
Ute Siemann-HarmsDepartment of Dermatology and Venereology, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany.
Katharina HerbergerDepartment of Laser and Aesthetics, Department of Dermatology and Venereology, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyaluronic acid (HA)-based injectables are generally considered safe. However, short- and long-term complications may occur.

objectiveTo evaluate complications related to soft-tissue augmentation presented to the Department of Dermatology at a university hospital. MATERIALS AND

methodsA retrospective analysis was conducted using electronic medical records from January 2019 to January 2025. Adverse events related to HA-based injectables, their management, and outcomes were identified and evaluated.

resultsThirty-one patients (mean age: 50.4 years) were included in the analysis. Injections have been administered by cosmeticians (2/31), nonmedical practitioners (2/31), or individuals of unknown qualification. The most common complications were biofilm formation and chronic immune reactions, followed by abscesses, Tyndall effect, vascular occlusion, and filler migration. Over half of the products involved were either uncertified or of unknown origin.

conclusionThe findings highlight the need for qualified practitioners, careful product selection, and adherence to standardized techniques. Enhancing practitioner education, establishing evidence-based protocols, and strengthening regulatory oversight are essential to ensure patient safety in aesthetic medicine.

Indexed as

Cosmetic TechniquesDermal FillersHyaluronic AcidInjection Site ReactionAbscessAdultAgedFemaleForeign-Body MigrationHumansMaleMiddle AgedRetrospective StudiesDermal FillersHyaluronic Acidaesthetic medicinefiller complicationsinjectablesvascular occlusion

Identifiers

PMID41555790
PMCPMC12817018

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.