Evidence map›Paper›PMID 41555703›Full record

ArticleMolecular reproduction and development2026

Cold Shock Compromises the Electrically Mediated Block to Polyspermy in Lytechinus variegatus Eggs.

Pedro I Ivonnet, Lukas Chambers, Lisa Künzi, Gabriel Garcia

Abstract read
In one paragraph

Article in Molecular reproduction and development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pedro I IvonnetDepartment of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-3527-674X
Lukas ChambersDepartment of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA.
Lisa KünziDepartment of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA.
Gabriel GarciaDepartment of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

National Science Foundation 9630380
6 · The paper itself

Abstract

Exposure to low temperature prior to insemination increases the likelihood of polyspermy in Lytechinus variegatus eggs. Electrophysiological recordings reveal that cold shock partially disrupts the egg's action potential, producing a subthreshold depolarization during the fertilization response. This attenuated shift in membrane potential appears insufficient to activate the fast block to polyspermy, allowing entry of multiple sperm. These findings identify a temperature-sensitive vulnerability in the electrical barrier to polyspermy in sea urchin eggs.

Indexed as

Action PotentialsCold-Shock ResponseFertilizationLytechinusOvumSpermatozoaAnimalsCold TemperatureFemaleMaleMembrane Potentialsaction potentialcold shockelectrical continuityfertilizationpolyspermy

Identifiers

PMID41555703
PMCPMC12816943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.