ArticleAmerican journal of epidemiology2026
The role of institutional trust in shaping the relationship between vaccine concerns and ongoing COVID-19 vaccination in a US national cohort.
Article in American journal of epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Concerns about vaccine safety and efficacy and institutional trust are well-established determinants of vaccine uptake, yet little is known about the extent to which institutional trust buffers or amplifies the behavioral effects of vaccine-related uncertainty. Using data from 4,253 adults in the CHASING COVID Cohort who completed their primary vaccine series, we examined whether trust in public health institutions or healthcare providers modified the association between vaccine concerns and receipt of an additional COVID-19 vaccine dose. Adjusted log-binomial regression models estimated risk ratios (aRRs) and 95% CIs, with effect modification assessed on multiplicative and additive scales. The association between not endorsing vaccine concerns and continued vaccination was stronger among those without trust in public health institutions (aRR = 2.38 [95% CI, 1.90-2.97]) than among those with trust (aRR = 1.34 [95% CI, 1.22-1.46]), while antagonism on the additive scale (RERI = $-$0.68; P <.01) indicated overlapping pathways as having no vaccine concerns added little to the likelihood of continued vaccination among those with trust in public health institutions. Provider trust showed modest additive effects (RERI = 0.16; P = .08), suggesting greater-than-additive influences. Together, findings highlight institutional trust as an important contextual determinant shaping how vaccine-related beliefs are enacted and underscoring its importance for promoting ongoing vaccination uptake.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.