Evidence map›Paper›PMID 41555679›Full record

SynthesisAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2026

Impact of Esophageal Temperature Monitoring on Esophageal Injury in PVI: A Systematic Review and Meta-Analysis.

Saad Manzoor, Mounika Kotte, Jahanzeb Malik, Bhavna Singla, Shivam Singla, Muhammad Subhan, Fnu Sandesh, Pooja Kumari, Abdullah Ashraf, Abida Perveen

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Impact of Esophageal Temperature Monitoring on Esophageal Injury in PVI: A Systematic Review and Meta-Analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Saad ManzoorDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Mounika KotteDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Jahanzeb MalikDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Bhavna SinglaDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Shivam SinglaDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Muhammad SubhanDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Fnu SandeshDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Pooja KumariDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.
Abdullah AshrafDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.ORCID 0009-0003-0638-8421
Abida PerveenDepartment of Medicine, Ibn e Seena Hospital, Kabul, Afghanistan.ORCID 0009-0002-3310-5442

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis meta-analysis aimed to evaluate the impact of esophageal temperature monitoring (ETM) on the incidence of esophageal injury during cryoballoon ablation (CBA) for atrial fibrillation (AF).

methodsA systematic search identified randomized controlled and observational studies comparing CBA procedures performed with versus without ETM. Data on study design, patient characteristics, procedural details, and esophageal outcomes were extracted. The primary endpoint was the incidence of endoscopically detected esophageal lesions (EDEL). Secondary outcomes included severe ulceration, symptomatic esophageal thermal injury (ETI), and atrioesophageal fistula (AEF). Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled using a random-effects model. Risk of bias was assessed according to Cochrane guidelines, and publication bias was evaluated with funnel plots.

resultsFour studies comprising 269 patients were included. ETM significantly reduced the risk of EDEL compared with no ETM (pooled OR 0.57, 95% CI 0.39-0.85), with low to moderate heterogeneity. Subgroup analyses confirmed consistent benefits across randomized and observational designs. Severe esophageal ulceration and symptomatic ETI were infrequent, and no AEF cases were reported. Funnel plot analysis indicated no major publication bias.

conclusionETM significantly lowers the incidence of esophageal injury during CBA and should be considered a routine safety measure to improve procedural outcomes.

Indexed as

Atrial FibrillationBody TemperatureEsophagusMonitoring, IntraoperativeHumansatrial fibrillationcryoballoon ablationesophageal injuryesophageal temperature monitoringmeta‐analysis

Identifiers

PMID41555679
PMCPMC12816882

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.