ArticleClinical and translational science2026
Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology.
Article in Clinical and translational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinical Characteristics, Molecular Diagnosis, and Drug Resistance Profiles of Nontuberculous Mycobacteria Infections: A Retrospective Analysis Using PCR Melting Curve Technology.Clinical and translational science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nontuberculous mycobacteria (NTM) are emerging global pathogens. This study aimed to analyze the clinical features, species distribution, and drug resistance profiles of NTM infections in a northern Chinese hospital. A retrospective cohort study included 1769 patients with suspected mycobacterial infection from August 2023 to July 2025. PCR melting curve analysis (PCR-MCA) was used for initial screening, with confirmation by targeted next-generation sequencing (tNGS). Confirmed cases were classified as localized or disseminated disease. Among 60 confirmed NTM cases, 48 were localized (mainly pulmonary) and 12 were disseminated. The predominant species in localized disease were Mycobacterium intracellulare (35.4%) and Mycobacterium abscessus (35.4%), while disseminated cases were primarily caused by M. intracellulare, Mycobacterium avium, and Mycobacterium kansasii. Localized disease presented mainly with cough and expectoration (95.8%), whereas fever was common in disseminated infections (83.3%, p < 0.001). Key risk factors included prior tuberculosis, bronchiectasis, and immunodeficiency. Time to diagnosis was significantly longer in localized cases (10.59 ± 17.05 months) than disseminated (1.83 ± 1.47 months). Drug resistance rates varied significantly among species. The M. avium complex (MAC) predominates in NTM disease. Species identification and drug susceptibility testing are essential for guiding targeted therapy due to non-specific symptoms and species-dependent resistance patterns.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.