ArticleBiotechnology and applied biochemistry2026
Cost-Effective and User-Friendly Pencil Graphite Electrode Immunosensor for Label-Free Detection of Carcinoembryonic Antigen.
Article in Biotechnology and applied biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We present a novel, cost-effective sensor for carcinoembryonic antigen (CEA) detection utilizing a pencil graphite electrode (PGE) in combination with electrochemical impedance spectroscopy (EIS), which offers high sensitivity and selectivity. Anti-CEA/AuNPs/PGE was successfully illustrated as a label-free impedimetric immunosensor for the detection of CEA. Through EIS, we observed distinct impedance changes upon CEA binding, enabling real-time detection with high reproducibility and low interference from non-target molecules. Due to its satisfying impedimetric response, this new immunosensor demonstrated that it can be used for high-performance detection of CEA with a wide linear range extending from 13.2 to 1 × 10
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